Terbogrel (
INN
Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they also provided accommo ...
) is an experimental drug that has been studied for its potential to prevent the vasoconstricting and platelet-aggregating action of
thromboxane
Thromboxane is a member of the family of lipids known as eicosanoids. The two major thromboxanes are thromboxane A2 and thromboxane B2. The distinguishing feature of thromboxanes is a 6-membered ether-containing ring.
Thromboxane is named for i ...
s. Terbogrel is an orally available
thromboxane A2 receptor antagonist and a
thromboxane A synthase inhibitor.
The drug was
developed by
Boehringer Ingelheim.
A
phase 2 clinical trial of terbogrel was discontinued due to its induction of leg pain.
See also
*
Ramatroban
References
{{Prostanoidergics
Antiplatelet drugs
3-Pyridyl compounds
Guanidines
Nitriles
Tert-butyl compounds