Dimethyladenosine transferase 2; transcription factor B2, mitochondrial is an

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...

that in humans is encoded by the ''TFB2M''

gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...

. This protein is a transcription initiation factor for the mitochondrial RNA polymerase,

POLRMT POLRMT is a symbol of RNA polymerase mitochondrial It is a DNA-directed RNA polymerase, mitochondrial is an enzyme that in humans is encoded by the ''POLRMT'' gene. Function This gene encodes a mitochondrial DNA-directed RNA polymerase. The gen ...

. Its paralog

TFB1M Dimethyladenosine transferase 1, mitochondrial; Transcription factor B1, mitochondrial is a mitochondrial enzyme that in is encoded by the ''TFB1M'' gene. TFB1M is a mitochondrial methyltransferase, which uses S-adenosyl methionine to dimethylate ...

can perform a similar function, but only ''

in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called " test-tube experiments", these studies in biology ...

''.

References

Further reading