TCPy or 3,5,6-trichloro-2-pyridinol is a cyclic hydrocarbon, specifically a

chlorinated In chemistry, halogenation is a chemical reaction which introduces one or more halogens into a chemical compound. Halide-containing compounds are pervasive, making this type of transformation important, e.g. in the production of polymers, drugs. ...

version of

2-pyridone 2-Pyridone is an organic compound with the formula . It is a colourless solid. It is well known to form hydrogen bonded dimers and it is also a classic case of a compound that exists as tautomers. Tautomerism The second tautomer is 2-hydroxy ...

. Pesticides can be a precursor to TCPy. TCPy is a metabolite of the herbicide

triclopyr Triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid) is an organic compound in the pyridine group that is used as a systemic foliar herbicide and fungicide. History Triclopyr triethylammonium (TEA) was first registered in 1979 in the United ...

, and of the insecticides

chlorpyrifos Chlorpyrifos (CPS), also known as chlorpyrifos ethyl, is an organophosphate pesticide that has been used on crops, animals, in buildings, and in other settings, to kill several pests, including insects and worms. It acts on the nervous systems ...

and chlorpyrifos-methyl. A study in Massachusetts reported a correlation between exposure to TCPy and lower

testosterone Testosterone is the primary male sex hormone and androgen in Male, males. In humans, testosterone plays a key role in the development of Male reproductive system, male reproductive tissues such as testicles and prostate, as well as promoting se ...

levels in men. According to this source, exposure is "widespread" and of "potential public health importance".

References

{{Insecticides Chloroarenes 2-Pyridones