Sunil Kumar Verma
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Sunil Kumar Verma (28September 1974 - 31 May 2021), was an Indian biologist and a principal scientist at the
Centre for Cellular and Molecular Biology The Centre for Cellular and Molecular Biology ( hi, कोशिकीय एवं आण्विक जीवविज्ञान केंद्र, IAST: ''Kośikīya evam āṇavik jīvavijñāna kendra'') or CCMB is an Indian fundamen ...
,
Hyderabad Hyderabad ( ; , ) is the capital and largest city of the Indian state of Telangana and the ''de jure'' capital of Andhra Pradesh. It occupies on the Deccan Plateau along the banks of the Musi River (India), Musi River, in the northern part ...
, India. Verma was primarily known for his contributions to the development of "universal primer technology", a first generation
DNA barcoding DNA barcoding is a method of species identification using a short section of DNA from a specific gene or genes. The premise of DNA barcoding is that by comparison with a reference library of such DNA sections (also called "sequences"), an indiv ...
method, that can identify any bird, fish, reptile or mammal from a small biological sample, and satisfy legal evidence requirements in a court of law. This technology has revitalised the field of wildlife forensics and is now routinely used across India to provide a species identification service in cases of wildlife crime. This approach of species identification is now known as "DNA barcoding" across the world. Verma received his
D.Phil. A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is ...
in
medical oncology Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ó ...
from the
University of Oxford , mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor ...
, and had worked in the areas of
signal transduction Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellula ...
in cancer and on molecular biology applications in
wildlife conservation Wildlife conservation refers to the practice of protecting wild species and their habitats in order to maintain healthy wildlife species or populations and to restore, protect or enhance natural ecosystems. Major threats to wildlife include habita ...
. He was the recipient of several national awards, including the 2008 CSIR Technology Award, the 2009 NRDC Meritorious Invention Award and the 2009 BioAsia Innovation Award in recognition of his contribution to Indian science and technology. He died on May 31, 2021, due to COVID-19 pneumonia.


Education and research career


Early life and education

Verma was born in a small village in the northern Indian state of
Uttar Pradesh Uttar Pradesh (; , 'Northern Province') is a state in northern India. With over 200 million inhabitants, it is the most populated state in India as well as the most populous country subdivision in the world. It was established in 1950 ...
. Verma grew up primarily in Tikri and up to the twelfth standard studied at the government school in Tikri. After completing his twelfth standard in the science group from this school in 1991, he attended the G. B. Pant University of Agriculture and Technology, Pantnagar to complete his Bachelor of Science in agriculture and animal husbandry.


Research career

Verma started his research career at G. B. Pant University of Agriculture and Technology, Pantnagar, where he worked on the
DNA fingerprinting DNA profiling (also called DNA fingerprinting) is the process of determining an individual's DNA characteristics. DNA analysis intended to identify a species, rather than an individual, is called DNA barcoding. DNA profiling is a forensic tec ...
of Indian scented
basmati Basmati, , is a variety of long, slender-grained aromatic rice which is traditionally grown in India, Pakistan, and Nepal.
rice for identification of duplicate accessions. In 1998, Verma was appointed as a scientist at the
Centre for DNA Fingerprinting and Diagnostics The Centre for DNA Fingerprinting and Diagnostics (CDFD) is an Indian biotechnology research centre, located in Hyderabad, India, operated by the Department of Biotechnology, Ministry of Science and Technology, Government of India. CDFD is a Sun ...
(CDFD) where he continued his research on the DNA-based identification system, and in 1999, he received the Emerging Forensic Scientist Continental Award from the International Association of Forensic Sciences at the
University of California The University of California (UC) is a public land-grant research university system in the U.S. state of California. The system is composed of the campuses at Berkeley, Davis, Irvine, Los Angeles, Merced, Riverside, San Diego, San Francisco, ...
, USA for his work on DNA
microsatellite A microsatellite is a tract of repetitive DNA in which certain DNA motifs (ranging in length from one to six or more base pairs) are repeated, typically 5–50 times. Microsatellites occur at thousands of locations within an organism's genome. ...
based identification of wild animals. In 2000, Verma was appointed as a scientist at the
Centre for Cellular and Molecular Biology The Centre for Cellular and Molecular Biology ( hi, कोशिकीय एवं आण्विक जीवविज्ञान केंद्र, IAST: ''Kośikīya evam āṇavik jīvavijñāna kendra'') or CCMB is an Indian fundamen ...
, where in 2001, he and
Lalji Singh Lalji Singh FNA, FASc (5 July 1947 – 10 December 2017) was an Indian scientist who worked in the field of DNA fingerprinting technology in India, where he was popularly known as the "Father of Indian DNA fingerprinting". Singh also worke ...
invented universal primer technology for wildlife identification, for which he later received a number of international patents, and several national awards including the CSIR Technology Award in 2008 (jointly conferred to Verma and
Lalji Singh Lalji Singh FNA, FASc (5 July 1947 – 10 December 2017) was an Indian scientist who worked in the field of DNA fingerprinting technology in India, where he was popularly known as the "Father of Indian DNA fingerprinting". Singh also worke ...
), the 2009 NRDC Award (jointly conferred on Verma and Singh) and the BioAsia Innovation Award in 2009. In 2003, Verma received a Lindau Fellowship to represent Indian scholars at the
Lindau Nobel Laureate Meetings The Lindau Nobel Laureate Meetings are annual scientific conferences held in Lindau, Bavaria, Germany, since 1951. Their aim is to bring together Nobel laureates and young scientists to foster scientific exchange between different generations, ...
in physiology and medicine. During the same year, he also received a
Commonwealth Scholarship The Commonwealth Scholarship and Fellowship Plan (CSFP) is an international programme under which Commonwealth governments offer scholarships and fellowships to citizens of other Commonwealth countries. History The plan was originally proposed b ...
to carry out his
doctoral studies A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is a ...
at the
University of Oxford , mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor ...
. Verma completed his
D.Phil. A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is ...
in
medical oncology Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ó ...
at the
University of Oxford , mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor ...
in 2007, and in January 2008 returned to India to continue his work at the CCMB. In 2010, he subsequently became principal scientist at the CCMB and , he remains in that position. Verma was a visiting fellow at the
Max Planck Institute for Infection Biology The Max Planck Institute for Infection Biology (MPIIB) is a non-university research institute of the Max Planck Society located in the heart of Berlin in Berlin-Mitte. It was founded in 1993. Arturo Zychlinsky is currently the Managing Director ...
during 2010–2013. Starting in 2010, he is a research ambassador for the DAAD to promote bidirectional research collaboration between India and Germany. Along with his team, Verma's research in the area of
wildlife conservation Wildlife conservation refers to the practice of protecting wild species and their habitats in order to maintain healthy wildlife species or populations and to restore, protect or enhance natural ecosystems. Major threats to wildlife include habita ...
led to the reclassification of the
pygmy hog The pygmy hog (''Porcula salvania'') is the rarest species of pig in the world today, and is the only species in the genus ''Porcula''. It is also the smallest species of pig in the world, with its piglets being small enough to fit in one's pock ...
, an endangered endemic species, from ''Sus salvanius'' to ''Porcula salvania''


2015 Nobel Prize Controversy

In 2015 Verma claimed that the malaria treatment drug
artemisinin Artemisinin () and its semisynthetic derivatives are a group of drugs used in the treatment of malaria due to ''Plasmodium falciparum''. It was discovered in 1972 by Tu Youyou, who shared the 2015 Nobel Prize in Physiology or Medicine for her dis ...
(initially extracted from ''Artemisia annua'', later synthesized), the discovery of which earned Chinese scientist
Tu Youyou Tu Youyou (; born 30 December 1930) is a Chinese pharmaceutical chemist and malariologist. She discovered artemisinin (also known as , ) and dihydroartemisinin, used to treat malaria, a breakthrough in twentieth-century tropical medicine, sa ...
the Lasker Award in 2011 and the
Nobel Prize in Physiology or Medicine The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, accord ...
in 2015, has roots in older traditional medicine from India under the name artemisin, associated with a related Indian plant species (Hindi: Ajwain) and previously identified as fever-treating. Verma argued that in order to fairly implement the provisions of Article 10 of
Nagoya Protocol The Nagoya Protocol on Access to Genetic Resources and the Fair and Equitable Sharing of Benefits Arising from their Utilization to the Convention on Biological Diversity, also known as the Nagoya Protocol on Access and Benefit Sharing (ABS) is a ...
on equitable sharing of benefits derived from the utilization of genetic resources and traditional knowledge associated with the genetic resources (such as a plant-based medicine that arises based on the traditional knowledge on the usage of the specific plant or closely related plant species), no single person or country must be allowed to take credit for a genetic resource, or associated traditional knowledge if that previously existed in many countries, merely due to absence of proper documentation, or the inability of a specific country to claim rights on its traditional knowledge due to various reasons such as absence of legal framework.


Universal primer technology

In March 2001, Verma and
Lalji Singh Lalji Singh FNA, FASc (5 July 1947 – 10 December 2017) was an Indian scientist who worked in the field of DNA fingerprinting technology in India, where he was popularly known as the "Father of Indian DNA fingerprinting". Singh also worke ...
claimed to have invented a method that they called "universal primer technology", which allowed the identification of any unknown biological sample and its assignment to a known species source. Through its ability to work across a large range of animal species, universal primer technology can identify any bird, fish, reptile or mammal and satisfy legal evidence requirements in a court of law. Patents relating to this invention have been filed in several countries and the research papers published in various journals. This technique of CSIR-CCMB revitalised the field of wildlife forensics. It is currently being used routinely in LaCONES at the CSIR-CCMB to provide a wildlife forensics service across India in cases pertaining to
wildlife crime Environmental crime is an illegal act which directly harms the environment. These illegal activities involve the environment, wildlife, biodiversity and natural resources. International bodies such as, G8, Interpol, European Union, United Nation ...
. Verma's and Singh's contribution to the development of universal primer technology has been recognised by the Indian minister of Science and Technology and the
Ministry of Earth Sciences The Ministry of Earth Sciences was formed on 29 January 2006 from a merger of the India Meteorological Department (IMD), the National Centre for Medium Range Weather Forecasting (NCMRWF), the Indian Institute of Tropical Meteorology (IITM), Pune ...
in a written report to the
Lok Sabha The Lok Sabha, constitutionally the House of the People, is the lower house of India's bicameral Parliament, with the upper house being the Rajya Sabha. Members of the Lok Sabha are elected by an adult universal suffrage and a first-past ...
. Universal primer technology was also used by Therion International, an independent animal testing lab in New York, to uncover the noted seafood scandal in Florida and other parts of America. Several undercover investigations carried out by the '' ABC7 Whistleblower'' and WKRG News5 investigators, revealed that almost half of the seafood was inaccurately labelled as a more expensive variety. This method of species identification used by the Therion International to uncover the seafood scam, was cited as "gold standard" by various labs worldwide.


Universal primer technology and DNA barcoding

In February 2015, a credit dispute between universal primer technology and
DNA barcoding DNA barcoding is a method of species identification using a short section of DNA from a specific gene or genes. The premise of DNA barcoding is that by comparison with a reference library of such DNA sections (also called "sequences"), an indiv ...
came to light. Verma has argued that
DNA barcoding DNA barcoding is a method of species identification using a short section of DNA from a specific gene or genes. The premise of DNA barcoding is that by comparison with a reference library of such DNA sections (also called "sequences"), an indiv ...
, a technique independently described by zoologist Paul D N Hebert in 2003, is essentially the same as universal primer technology (UPT) and that both utilize standardized, short stretch of DNA from mitochondrial genome, amplified using the specific universal primers, to assign the identity of an unknown biological sample to a particular species. Verma claimed that UPT was described earlier than DNA barcoding in his patents, and publication; therefore, it should be fairly credited. However, Hebert argued that he was not aware of UPT because its patents were not visible to the broader scientific community due to a substantial interval from its filing in 2001 to grant in 2006.


Literature

Verma has written several collections of
Hindi Hindi (Devanāgarī: or , ), or more precisely Modern Standard Hindi (Devanagari: ), is an Indo-Aryan language spoken chiefly in the Hindi Belt region encompassing parts of northern, central, eastern, and western India. Hindi has been de ...
poetry on social issues such as the
2012 Delhi gang rape The 2012 Delhi gang rape and murder, commonly known as the Nirbhaya case, involved a rape and fatal assault that occurred on 16 December 2012 in Munirka, a neighbourhood in South West Delhi. The incident took place when Jyoti Singh, a 22-year ...
. In 2014, his work was showcased in Hyderabad by the Association of British Scholars.


Awards and honors

Some notable fellowships and awards conferred to Verma are as follows: * IEmerging Forensic Scientist Continental Award (1999) from the International Association of Forensics Sciences * Lindau Fellowship (2003) to represent Indian scholars at the
Lindau Nobel Laureate Meetings The Lindau Nobel Laureate Meetings are annual scientific conferences held in Lindau, Bavaria, Germany, since 1951. Their aim is to bring together Nobel laureates and young scientists to foster scientific exchange between different generations, ...
in Physiology and Medicine in 2003 *
Commonwealth Scholarship The Commonwealth Scholarship and Fellowship Plan (CSFP) is an international programme under which Commonwealth governments offer scholarships and fellowships to citizens of other Commonwealth countries. History The plan was originally proposed b ...
(2003) * CSIR Technology Award for Life Sciences" (2008), Jointly conferred to Sunil Kumar Verma and
Lalji Singh Lalji Singh FNA, FASc (5 July 1947 – 10 December 2017) was an Indian scientist who worked in the field of DNA fingerprinting technology in India, where he was popularly known as the "Father of Indian DNA fingerprinting". Singh also worke ...
* NRDC Societal Invention Award (2009), Jointly conferred to Sunil Kumar Verma and
Lalji Singh Lalji Singh FNA, FASc (5 July 1947 – 10 December 2017) was an Indian scientist who worked in the field of DNA fingerprinting technology in India, where he was popularly known as the "Father of Indian DNA fingerprinting". Singh also worke ...
* The BioAsia Innovation Award (2009) * Fellowship of
Max Planck Institute for Infection Biology The Max Planck Institute for Infection Biology (MPIIB) is a non-university research institute of the Max Planck Society located in the heart of Berlin in Berlin-Mitte. It was founded in 1993. Arturo Zychlinsky is currently the Managing Director ...
Berlin (2010–2013) * Research ambassador of DAAD (2010-till death)


Selected publications

* * * * * *


References


External links


From the Editors desk: Two words of Grace for BioGov

Shraddhanjali: Collection of some Hindi Poems written by Sunil Verma

Nirbhaya: Wo Desh Ki Beti collections of Hindi Poems written by Sunil Verma
{{DEFAULTSORT:Verma, Sunil 1974 births Living people Alumni of Green College, Oxford 20th-century Indian zoologists Scientists from Uttar Pradesh