Star Anise
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''Illicium verum'' is a medium-sized
evergreen In botany, an evergreen is a plant which has foliage that remains green and functional through more than one growing season. This also pertains to plants that retain their foliage only in warm climates, and contrasts with deciduous plants, whic ...
tree native to northeast
Vietnam Vietnam or Viet Nam ( vi, Việt Nam, ), officially the Socialist Republic of Vietnam,., group="n" is a country in Southeast Asia, at the eastern edge of mainland Southeast Asia, with an area of and population of 96 million, making ...
and southwest China. A spice commonly called star anise, staranise, star anise seed, star aniseed, star of anise, Chinese star anise, or badian that closely resembles
anise Anise (; '), also called aniseed or rarely anix is a flowering plant in the family Apiaceae native to Eurasia. The flavor and aroma of its seeds have similarities with some other spices and herbs, such as star anise, fennel, licorice, and t ...
in flavor is obtained from the star-shaped pericarps of the fruit of ''I. verum'' which are harvested just before ripening. Star anise oil is a highly fragrant oil used in cooking, perfumery, soaps, toothpastes, mouthwashes, and skin creams. Until 2012, when they switched to using a bacterial source, Roche Pharmaceuticals used up to 90% of the world's annual star anise crop to produce shikimic acid, a chemical intermediate used in the synthesis of oseltamivir (Tamiflu).


Etymology and nomenclature

''Illicium'' comes from the
Latin Latin (, or , ) is a classical language belonging to the Italic languages, Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through ...
''illicio'' meaning "entice" or "seduce".Gledhill, David (2008). "The Names of Plants". Cambridge University Press. (hardback), (paperback). pp 210, 400 ''Verum'' means "true" or "genuine". The name "badian" appears to derive, via French ''badiane'', from the apparently descriptive Chinese name for it, 八角,
pinyin Hanyu Pinyin (), often shortened to just pinyin, is the official romanization system for Standard Mandarin Chinese in China, and to some extent, in Singapore and Malaysia. It is often used to teach Mandarin, normally written in Chinese fo ...
: ''bājiǎo'', lit. "eight horns". However, a derivation from the Persian ''bādiyān,'' "fennel", exists, with the Oxford English Dictionary indicating that its origin before that is unknown.


Description

Leaves are aromatic, simple and lanceolate, obovate-elliptic or elliptic, size of 5–15 cm × 2–5 cm, coriaceous to thickly coriaceous. The leaves are 5–15 cm × 1.5–5 cm, apex acute, lower side pubescent. Flowers are solitary, bisexual, pink to dark red, axillary or subterminal. The perianth has lobes 7–12, arranged spirally; stamens number of 11–20, arranged spirally, with short, thick filaments; carpels usually 8, free, arranged in a single whorl. Flower peduncle size is 1.5–4 cm, tepals number range from seven to twelve, and are broadly elliptic to broadly ovate, anthers size is 1–1.5 mm, pollen grains trisyncolpate. The fruit is a capsule-like follicetum, star-shaped, reddish- brown, consisting of six to eight follicles arranged in a whorl. Each follicle is boat-shaped, 1–2 cm long, rough and rigid, color reddish-brown, with 1 seed, opening along the ventral edge when ripe. carpels size of 10 mm long, boat-shaped; they are hard and wrinkled, containing one seed. Seeds are brown, compressed ovoid, smooth, shiny and brittle with approximate size of 8–9 mm × 6 mm. Differences with similar taxa: ''Illicium anisatum'' had smaller fruits that does not form a regular star due to the abortion of some carpels. Also fruit follicles are not swollen in the middle and had a more pointed apex. Also usually had more than 8 follicles and the fruit has weaker odour. The seeds in ''Illicium anisatum'' are flat or almost spherical.


Use


Culinary use

Star anise contains
anethole Anethole (also known as anise camphor) is an organic compound that is widely used as a flavoring substance. It is a derivative of phenylpropene, a type of aromatic compound that occurs widely in nature, in essential oils. It is in the class of phe ...
, the same compound that gives the unrelated
anise Anise (; '), also called aniseed or rarely anix is a flowering plant in the family Apiaceae native to Eurasia. The flavor and aroma of its seeds have similarities with some other spices and herbs, such as star anise, fennel, licorice, and t ...
its flavor. Recently, star anise has come into use in the
West West or Occident is one of the four cardinal directions or points of the compass. It is the opposite direction from east and is the direction in which the Sun sets on the Earth. Etymology The word "west" is a Germanic word passed into some ...
as a less expensive substitute for anise in baking, as well as in
liquor Liquor (or a spirit) is an alcoholic drink produced by distillation of grains, fruits, vegetables, or sugar, that have already gone through alcoholic fermentation. Other terms for liquor include: spirit drink, distilled beverage or h ...
production, most distinctively in the production of the
liqueur A liqueur (; ; ) is an alcoholic drink composed of spirits (often rectified spirit) and additional flavorings such as sugar, fruits, herbs, and spices. Often served with or after dessert, they are typically heavily sweetened and un-aged beyon ...
Galliano. Star anise enhances the flavour of meat. It is used as a spice in preparation of '' biryani'' and ''
masala chai Masala chai (, ; Urdu: مصالحہ چائے, Hindi: मसाला चाय) is an Indian tea beverage made by boiling black tea in milk and water with a mixture of aromatic herbs and spices. Originating in India the beverage has gained worl ...
'' all over the
Indian subcontinent The Indian subcontinent is a physiographical region in Southern Asia. It is situated on the Indian Plate, projecting southwards into the Indian Ocean from the Himalayas. Geopolitically, it includes the countries of Bangladesh, Bhutan, In ...
. It is widely used in
Chinese cuisine Chinese cuisine encompasses the numerous cuisines originating from China, as well as overseas cuisines created by the Chinese diaspora. Because of the Chinese diaspora and historical power of the country, Chinese cuisine has influenced many o ...
, and in Malay and
Indonesian cuisine Indonesian cuisine is a collection of various regional culinary traditions that formed the archipelagic nation of Indonesia. There are a wide variety of recipes and cuisines in part because Indonesia is composed of approximately 6,000 popula ...
s. It is widely grown for commercial use in China, India, and most other countries in Asia. Star anise is an ingredient of the traditional five-spice powder of Chinese cooking. It is also a major ingredient in the making of '' phở'', a Vietnamese noodle soup. It is also used in the French recipe of mulled wine, called ''vin chaud'' (hot wine). If allowed to steep in coffee, it deepens and enriches the flavor. The pods can be used in this manner multiple times by the pot-full or cup, as the ease of extraction of the taste components increases with the permeation of hot water.


Drug precursor

Star anise is the major source of the chemical compound shikimic acid, a primary
precursor Precursor or Precursors may refer to: * Precursor (religion), a forerunner, predecessor ** The Precursor, John the Baptist Science and technology * Precursor (bird), a hypothesized genus of fossil birds that was composed of fossilized parts of u ...
in the
pharmaceutical A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the medical field and ...
synthesis of the anti
influenza Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptom ...
drug oseltamivir (Tamiflu). An industrial method for the production of shikimic acid using
fermentation Fermentation is a metabolic process that produces chemical changes in organic substrates through the action of enzymes. In biochemistry, it is narrowly defined as the extraction of energy from carbohydrates in the absence of oxygen. In food p ...
of '' E. coli'' bacteria was discovered in 2005, and applied in the 2009 swine flu pandemic to address Tamiflu shortages, also causing price increases for star anise as a
raw material A raw material, also known as a feedstock, unprocessed material, or primary commodity, is a basic material that is used to produce goods, finished goods, energy, or intermediate materials that are feedstock for future finished products. As feeds ...
of shikimic acid. As of 2018, fermentation of ''E. coli'' was the manufacturing process of choice to produce shikimic acid for synthesis of Tamiflu. Study shows star anise can be used as anti quorum sensing and anti-biofilm agent in food matrix.


Toxicity of related species

''Illicium verum'' is not toxic. However, other related species are toxic.
Japanese star anise ''Illicium anisatum'', with common names Japanese star anise, Aniseed tree, and sacred Anise tree, known in Japan as , is a tree closely related to the Chinese star anise (''Illicium verum)''. Since it is highly toxic, the fruit is not edible; ...
(''Illicium anisatum''), a similar tree, is highly toxic and inedible; in Japan, it has instead been burned as
incense Incense is aromatic biotic material that releases fragrant smoke when burnt. The term is used for either the material or the aroma. Incense is used for aesthetic reasons, religious worship, aromatherapy, meditation, and ceremony. It may also b ...
. Cases of illness, including "serious
neurological Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal c ...
effects, such as seizures", reported after using star anise tea, may be a result of deliberate economically motivated adulteration with this species. Japanese star anise contains the
neurotoxin Neurotoxins are toxins that are destructive to nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological insultsSpencer 2000 that can adversely affect function in both developing and mature nerv ...
anisatin, which also causes severe
inflammation Inflammation (from la, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molec ...
of the kidneys (
nephritis Nephritis is inflammation of the kidneys and may involve the glomeruli, tubules, or interstitial tissue surrounding the glomeruli and tubules. It is one of several different types of nephropathy. Types * Glomerulonephritis is inflammation ...
), urinary tract, and
digestive organs The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and ...
when ingested. Swamp star anise ''
Illicium parviflorum ''Illicium parviflorum'', commonly known as yellow anisetree, yellow-anise, swamp star-anise,ISO 676 ISO is the most common abbreviation for the International Organization for Standardization. ISO or Iso may also refer to: Business and finance * Iso (supermarket), a chain of Danish supermarkets incorporated into the SuperBest chain in 2007 * Iso ...
:1995 – contains the information about the nomenclature of the variety and cultivars


Identification

* Refer to the 4th edition of the ''
European Pharmacopoeia The ''European Pharmacopoeia'' (''Pharmacopoeia Europaea'', ''Ph. Eur.'') is a major regional pharmacopoeia which provides common quality standards throughout the pharmaceutical industry in Europe to control the quality of medicines, and the ...
'' (1153)


Differentiation from other species

Joshi ''et al.'' have used
fluorescent microscopy A fluorescence microscope is an optical microscope that uses fluorescence instead of, or in addition to, scattering, reflection, and attenuation or absorption, to study the properties of organic or inorganic substances. "Fluorescence microsc ...
and
gas chromatography Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. Typical uses of GC include testing the purity of a particular substanc ...
to distinguish the species, while Lederer ''et al.'' employed thin layer chromatography with
HPLC High-performance liquid chromatography (HPLC), formerly referred to as high-pressure liquid chromatography, is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to p ...
- MS/MS.


Specifications

* ISO 11178:1995 - a specification for its dried fruits


References

{{Taxonbar, from=Q2878644 verum Spices Indian spices Non-timber forest products Medicinal plants of Asia Trees of China Trees of Vietnam Taxa named by Joseph Dalton Hooker