Stanford Cade
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Sir Stanford Cade (formerly Kadinsky), (22 March 1895 – 19 September 1973) was a British surgeon of Russian origin, who pioneered the combined use of surgery and radiotherapy in the treatment of
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
in
England England is a country that is part of the United Kingdom. It shares land borders with Wales to its west and Scotland to its north. The Irish Sea lies northwest and the Celtic Sea to the southwest. It is separated from continental Europe b ...
. He was born in what was then the
Russian Empire The Russian Empire was an empire and the final period of the Russian monarchy from 1721 to 1917, ruling across large parts of Eurasia. It succeeded the Tsardom of Russia following the Treaty of Nystad, which ended the Great Northern War. ...
, educated in Antwerp, and started his medical training in
Brussels Brussels (french: Bruxelles or ; nl, Brussel ), officially the Brussels-Capital Region (All text and all but one graphic show the English name as Brussels-Capital Region.) (french: link=no, Région de Bruxelles-Capitale; nl, link=no, Bruss ...
. His training was interrupted by the
First World War World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...
, and he was evacuated to England. Cade's medical education continued at
Westminster Hospital Medical School The Westminster Hospital Medical School was formally founded in 1834 by George Guthrie, an ex-military surgeon – although students had been taken on at Westminster Hospital almost from the hospital's foundation in 1719 (the traditional name a ...
, and following qualification he did various jobs at
Westminster Hospital Westminster Hospital was a hospital in London, England, founded in 1719. In 1834 a medical school attached to the hospital was formally founded. In 1939 a newly built hospital and medical school opened in Horseferry Road, Westminster. In 1994 the ...
, finally being appointed consultant surgeon. He pioneered the combined use of
radium Radium is a chemical element with the symbol Ra and atomic number 88. It is the sixth element in group 2 of the periodic table, also known as the alkaline earth metals. Pure radium is silvery-white, but it readily reacts with nitrogen (rathe ...
or
X rays An X-ray, or, much less commonly, X-radiation, is a penetrating form of high-energy electromagnetic radiation. Most X-rays have a wavelength ranging from 10  picometers to 10 nanometers, corresponding to frequencies in the range 30&nbs ...
in the treatment of cancer. During the
Second World War World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposi ...
, Cade was a member of the Royal Air Force Volunteer Reserve. In addition to his medical work, he also advised on improvements in the design of the cockpits of fighter planes, for which he was awarded a knighthood. After the war, Cade's work led to him gaining several honours and appointments. Cade wrote two books on the treatment of cancer.


Early life and training

Stanford Cade, the son of a diamond merchant, was born in Dwinsk, then in the
Russian Empire The Russian Empire was an empire and the final period of the Russian monarchy from 1721 to 1917, ruling across large parts of Eurasia. It succeeded the Tsardom of Russia following the Treaty of Nystad, which ended the Great Northern War. ...
, now in Latvia. His family moved to St Petersburg, but at the age of eight he and his older brother were sent to school in Antwerp. In 1913 Cade commenced his medical studies at the University of Brussels. When the First World War started two years later he volunteered to serve in the Belgian Army, but when Antwerp was overrun he was evacuated to England. Cade could speak Russian, French, and German, but no English, and he was allowed to write his first medical examination, which he passed, in French. He went to
King's College, London King's College London (informally King's or KCL) is a public university, public research university located in London, England. King's was established by royal charter in 1829 under the patronage of George IV of the United Kingdom, King G ...
, and then won a scholarship to
Westminster Hospital Medical School The Westminster Hospital Medical School was formally founded in 1834 by George Guthrie, an ex-military surgeon – although students had been taken on at Westminster Hospital almost from the hospital's foundation in 1719 (the traditional name a ...
. Cade soon became fluent in speaking English, qualified as a doctor in 1917, and undertook a series of medical appointments at
Westminster Hospital Westminster Hospital was a hospital in London, England, founded in 1719. In 1834 a medical school attached to the hospital was formally founded. In 1939 a newly built hospital and medical school opened in Horseferry Road, Westminster. In 1994 the ...
. During this time, he became a British subject, and changed his surname from Kadinsky to Cade. He was appointed consultant surgeon at Westminster Hospital in 1924, and later became surgeon to the Radium Institute and to
Mount Vernon Hospital Mount Vernon Hospital is located in Northwood, an area of north-west Greater London. It is one of two hospitals run by The Hillingdon Hospitals NHS Foundation Trust. History The hospital was founded as The North London Hospital for Co ...
. Cade became a
Fellow of the Royal College of Surgeons Fellowship of the Royal Colleges of Surgeons (FRCS) is a professional qualification to practise as a senior surgeon in Ireland or the United Kingdom. It is bestowed on an intercollegiate basis by the four Royal Colleges of Surgeons (the Royal ...
in 1923, Fellow of the Royal College of Obstetricians and Gynaecologists in 1954, and
Fellow of the Royal College of Physicians The Royal College of Physicians (RCP) is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1 ...
in 1961.


Career

At an early stage in his career, Cade took an interest in
regional anaesthesia Local anesthesia is any technique to induce the absence of sensation in a specific part of the body, generally for the aim of inducing local analgesia, that is, local insensitivity to pain, although other local senses may be affected as well. It ...
, and in 1925 his first Hunterian lecture was given on this subject. Following visits to the Radium Institute in Paris, he was influenced by the pioneering work of
Claudius Regaud Claudius Regaud (born 30 January 1870 in Lyons, France; died 29 December 1940 in Couzon-au-Mont-d'Or, France) was a French doctor and biologist, one of the pioneers in radiotherapy at the Curie Institute. Scientific work In 1906, Regaud disco ...
in the treatment of cancer by radiotherapy. Cade developed the therapeutic use of radium and X rays, combining this with surgery, and became an expert in these techniques. Together with other colleagues, he opened the Radium Annex of Westminster Hospital in Hampstead. In line with his multidisciplinary approach to cancer treatment, Cade conducted combined clinics with radiotherapists. During the Second World War he became a member of the Royal Air Force Volunteer Reserve, eventually achieving the rank of air vice marshal. During his service Cade's activities were not confined to surgery; he took an interest in the cause of injury to pilots, suggesting changes to the design of fighter planes cockpits. These were accepted and resulted in a reduction of casualties. For this work he was appointed a Companion of the Order of the Bath, and at the end of the war he was awarded a knighthood as a Knight Commander of the Order of the British Empire, and was appointed as an honorary air commodore. Following the war Cade worked with the army and was appointed its honorary civilian consultant in radiotherapy. He was a member of the council of the
Royal College of Surgeons The Royal College of Surgeons is an ancient college (a form of corporation) established in England to regulate the activity of surgeons. Derivative organisations survive in many present and former members of the Commonwealth. These organisations a ...
, later becoming its vice-president, a member of its court of examiners, and was awarded its Guthrie Medal. Cade's work was recognised worldwide; he was given honorary memberships and gave lectures in countries including the US, Chile, France, Ireland, and Greece.


Personal life

In 1920 Cade married Margaret Hester Agate, from Paisley, Scotland, who was a nurse at Westminster Hospital. She died from
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
in 1951 in South Africa when they were visiting the country together. They had three daughters, one of whom became a radiotherapist.


Publications


Hunterian lectures

*1925 Regional anaesthesia *1933 The radiation treatment of cancer of the mouth and pharynx *1954 Adrenalectomy


Books

*1929 ''The Radium Treatment of Cancer'' *1940 ''Malignant Disease and its Treatment by Radium''


Notes


References


Further reading

* {{DEFAULTSORT:Cade, Stanford 1895 births 1973 deaths Alumni of King's College London Alumni of Westminster Hospital Medical School Belgian Army personnel Belgian Army personnel of World War I British oncologists Companions of the Order of the Bath English surgeons Fellows of the Royal College of Physicians Emigrants from the Russian Empire to the United Kingdom Honorary air commodores Knights Commander of the Order of the British Empire Naturalised citizens of the United Kingdom People from Daugavpils Royal Air Force air marshals of World War II Royal Air Force Volunteer Reserve personnel of World War II Emigrants from the Russian Empire to Belgium 20th-century surgeons