Spears House may refer to:
*
Spears House (Greenbrier, Arkansas), listed on the NRHP in Arkansas
*
Spears-Craig House, Danville, Kentucky,
listed on the NRHP in Kentucky
*
Jacob Spears Distillery, Shawhan, Kentucky,
listed on the NRHP in Kentucky
*
Jacob Spears House, Shawhan, Kentucky,
listed on the NRHP in Kentucky
*
Spears House (Concord, North Carolina),
listed on the NRHP in North Carolina
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