Serio may refer to:
*
Sério, a municipality in Rio Grande do Sul, Brazil
*
Serio (river)
The Serio ( Lombard: ''Sère'') is an Italian river that flows entirely within Lombardy, crossing the provinces of Bergamo and Cremona
Cremona (, also ; ; lmo, label= Cremunés, Cremùna; egl, Carmona) is a city and ''comune'' in northe ...
, a river in Lombardy, Italy
**
Cascate del Serio
*
11022 Serio, a main belt asteroid
People with the surname
*
José Sério (1922–2010), Portuguese footballer
*
Renato Serio (born 1946), Italian composer, conductor and arranger
*
Steve Serio (born 1987), American wheelchair basketball player
Fictional
*
Serio (HMX-13), a character from the visual novel ''
To Heart
''To Heart'' is a Japanese Eroge, adult visual novel developed by Leaf (company), Leaf and released on May 23, 1997 for Microsoft Windows, Windows. It was later Porting, ported to the PlayStation (console), PlayStation and given voice act ...
''
{{Disambiguation, surname