Serenus may refer to:
*Saint
Serenus the Gardener (Sirenatus, Cerneuf), also known as Serenus of Sirmium
*Saint
Serenus of Alexandria (died 202 AD), Egyptian martyr
*
Serenus Sammonicus
Quintus Serenus Sammonicus (died 212) was a Roman savant and tutor to Geta and Caracalla who became fatally involved in politics; he was also author of a didactic medical poem, '' Liber Medicinalis'' ("The Medical Book"; also known as ''De medici ...
, a Roman scholar
*
Serenus of Antinoöpolis, also known as Serenus of Antinoeia, a mathematician from
Antinoöpolis.
*
Serenus, a messiah claimant (circa 720)
*
Serenicus and
Serenidus of Saulges
{{hndis