Selected ion monitoring (SIM) is a
mass spectrometry scanning mode in which only a limited
mass-to-charge ratio range is transmitted/detected by the instrument, as opposed to the full
spectrum
A spectrum (plural ''spectra'' or ''spectrums'') is a condition that is not limited to a specific set of values but can vary, without gaps, across a continuum. The word was first used scientifically in optics to describe the rainbow of colors ...
range.
This mode of operation typically results in significantly increased sensitivity. Due to their inherent nature, this technique is most effective—and therefore most common—on
quadrupole mass spectrometers and
Fourier transform ion cyclotron resonance mass spectrometers.
See also
*
Selected reaction monitoring
Selected reaction monitoring (SRM), also called Multiple reaction monitoring, (MRM), is a method used in tandem mass spectrometry in which an ion of a particular mass is selected in the first stage of a tandem mass spectrometer and an ion product ...
References
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Mass spectrometry