Sebaceous hyperplasia
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Sebaceous hyperplasia is a disorder of the
sebaceous gland A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. In humans, sebaceous glands occur in the greatest nu ...
s in which they become enlarged, producing flesh-colored or yellowish, shiny, often umbilicated bumps on the face. Newly formed nodules often swell with sweating (which is pathognomonic for the condition), but this diminishes over time.
Sebaceous gland A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. In humans, sebaceous glands occur in the greatest nu ...
s are glands located within the
skin Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different de ...
and are responsible for secreting an oily substance named
sebum A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. In humans, sebaceous glands occur in the greatest nu ...
. They are commonly associated with hair follicles but they can be found in hairless regions of the skin as well. Their secretion lubricates the skin, protecting it from drying out or becoming irritated. Sebaceous hyperplasia generally affects newborns as well as middle-aged to elderly adults. The symptoms of this condition are 1–5 mm
papule A papule is a small, well-defined bump in the skin. It may have a rounded, pointed or flat top, and may have a dip. It can appear with a stalk, be thread-like or look warty. It can be soft or firm and its surface may be rough or smooth. Some h ...
s on the skin, mainly on the forehead, nose and cheeks, and seborrheic facial skin. The papules may be cauliflower-shaped. In infants,
acne Acne, also known as ''acne vulgaris'', is a long-term skin condition that occurs when dead skin cells and oil from the skin clog hair follicles. Typical features of the condition include blackheads or whiteheads, pimples, oily skin, and ...
is sometimes associated with sebaceous hyperplasia. File:Photography of sebaceous hyperplasia.jpg, Photography of sebaceous hyperplasia, showing a group of papules, in this case on the chest with linear distribution pattern. File:Dermoscopy of sebaceous hyperplasia.jpg, Dermoscopy of sebaceous hyperplasia. Note the aggregation of yellowish-white clods with linear vessels between or above the clods. File:High dynamic range dermoscopy of sebaceous hyperplasia.jpg, Dermoscopy of sebaceous hyperplasia with digital
high dynamic range High dynamic range (HDR) is a dynamic range higher than usual, synonyms are wide dynamic range, extended dynamic range, expanded dynamic range. The term is often used in discussing the dynamic range of various signals such as images, videos, au ...
. Note the multi-lobulated clods with central openings. File:Histopathology of sebaceous hyperplasia.jpg, H&E staining of biopsied lesion of sebaceous hyperplasia: Note the multiple, mature sebaceous lobules attached to the central dilated duct in the upper dermis. File:Malignant Melanoma right temple medial adjacent sebaceous hyperplasia right temple lateral.jpg, Sebaceous hyperplasia, lateral right temple marked for biopsy with adjacent malignant melanoma in situ, evolving, medial right temple File:Sebaceaous Hyperplasia Chronic folliculits Right Mid Chest.jpg, Sebaceous hyperplasia with surrounding chronic folliculitis, right mid chest


See also

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Sebaceous adenoma A sebaceous adenoma, a type of adenoma, a cutaneous condition characterized by a slow-growing tumor usually presenting as a pink, flesh-coloured, or yellow papule or nodule. James et al. 2006 Rapini et al. 2007 Significance Sebaceous adenomas, ...
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Sebaceous carcinoma Sebaceous carcinoma, also known as sebaceous gland carcinoma (SGc), sebaceous cell carcinoma, and meibomian gland carcinoma is an uncommon malignant cutaneous tumor. Most are typically about 1.4 cm at presentation. SGc originates from sebaceous ...
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Skin lesion A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of th ...


References


External links

Epidermal nevi, neoplasms, and cysts {{Epidermal-growth-stub