Sclerocornea is a congenital anomaly of the eye in which the

cornea The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Along with the anterior chamber and lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical ...

blends with sclera, having no clear-cut boundary. The extent of the resulting opacity varies from peripheral to total (''sclerocornea totalis''). The severe form is thought to be inherited in an autosomal recessive manner, but there may be another, milder form that is expressed in a dominant fashion. In some cases the patients also have abnormalities beyond the eye ( systemic), such as limb deformities and craniofacial and genitourinary defects. According to one tissue analysis performed after corneal transplantation, the sulfation pattern of keratan sulfate proteoglycans in the affected area is typical for corneal rather than scleral tissue. Sclerocornea may be concurrent with cornea plana. Sclera

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External links

Congenital Clouding of the Cornea
- eMedicine; by Noah S Scheinfeld, MD, JD, FAAD and Benjamin D Freilich, MD, FACS {{Congenital malformations and deformations of eye Eye diseases