Science and technology in the United States
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Science and technology in the United States has a long history, producing many important figures and developments in the field. The
United States of America The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territo ...
came into being around the
Age of Enlightenment The Age of Enlightenment or the Enlightenment; german: Aufklärung, "Enlightenment"; it, L'Illuminismo, "Enlightenment"; pl, Oświecenie, "Enlightenment"; pt, Iluminismo, "Enlightenment"; es, La Ilustración, "Enlightenment" was an intel ...
(1685 to 1815), an era in
Western philosophy Western philosophy encompasses the philosophy, philosophical thought and work of the Western world. Historically, the term refers to the philosophical thinking of Western culture, beginning with the ancient Greek philosophy of the Pre-Socratic p ...
in which writers and thinkers, rejecting the perceived
superstition A superstition is any belief or practice considered by non-practitioners to be irrational or supernatural, attributed to fate or magic, perceived supernatural influence, or fear of that which is unknown. It is commonly applied to beliefs ...
s of the past, instead chose to emphasize the intellectual, scientific and cultural life, centered upon the 18th century, in which reason was advocated as the primary source for legitimacy and authority. Enlightenment philosophers envisioned a "republic of science," where ideas would be exchanged freely and useful knowledge would improve the lot of all citizens. The
United States Constitution The Constitution of the United States is the supreme law of the United States of America. It superseded the Articles of Confederation, the nation's first constitution, in 1789. Originally comprising seven articles, it delineates the natio ...
itself reflects the desire to encourage scientific creativity. It gives the
United States Congress The United States Congress is the legislature of the federal government of the United States. It is Bicameralism, bicameral, composed of a lower body, the United States House of Representatives, House of Representatives, and an upper body, ...
the power "to promote the progress of science and useful arts, by securing for limited times to authors and inventors the exclusive right to their respective writings and discoveries." This clause formed the basis for the
U.S. patent Under United States law, a patent is a right granted to the inventor of a (1) process, machine, article of manufacture, or composition of matter, (2) that is new, useful, and non-obvious. A patent is the right to exclude others, for a limited ...
and
copyright A copyright is a type of intellectual property that gives its owner the exclusive right to copy, distribute, adapt, display, and perform a creative work, usually for a limited time. The creative work may be in a literary, artistic, educatio ...
systems, whereby creators of original art and technology would get a government granted monopoly, which after a limited period would become free to all citizens, thereby enriching the
public domain The public domain (PD) consists of all the creative work to which no exclusive intellectual property rights apply. Those rights may have expired, been forfeited, expressly waived, or may be inapplicable. Because those rights have expired ...
.


Early American science

In the early decades of its history, the United States was relatively isolated from
Europe Europe is a large peninsula conventionally considered a continent in its own right because of its great physical size and the weight of its history and traditions. Europe is also considered a Continent#Subcontinents, subcontinent of Eurasia ...
and also rather poor. At this stage, America's scientific infrastructure was still quite primitive compared to the long-established societies, institutes, and universities in Europe. Eight of America's founding fathers were scientists of some repute.
Benjamin Franklin Benjamin Franklin ( April 17, 1790) was an American polymath who was active as a writer, scientist, inventor, statesman, diplomat, printer, publisher, and political philosopher. Encyclopædia Britannica, Wood, 2021 Among the leading int ...
conducted a series of experiments that deepened human understanding of
electricity Electricity is the set of physical phenomena associated with the presence and motion of matter that has a property of electric charge. Electricity is related to magnetism, both being part of the phenomenon of electromagnetism, as describe ...
. Among other things, he proved what had been suspected but never before shown: that
lightning Lightning is a naturally occurring electrostatic discharge during which two electrically charged regions, both in the atmosphere or with one on the ground, temporarily neutralize themselves, causing the instantaneous release of an average ...
is a form of electricity. Franklin also invented such conveniences as bifocal eyeglasses. Franklin also conceived the mid-room furnace, the "Franklin Stove". However, Franklin's design was flawed, in that his furnace vented the smoke from its base: because the furnace lacked a chimney to "draw" fresh air up through the central chamber, the fire would soon go out. It took David R. Rittenhouse, another hero of early Philadelphia, to improve Franklin's design by adding an L-shaped exhaust pipe that drew air through the furnace and vented its smoke up and along the ceiling, then into an intramural chimney and out of the house.
Thomas Jefferson Thomas Jefferson (April 13, 1743 – July 4, 1826) was an American statesman, diplomat, lawyer, architect, philosopher, and Founding Fathers of the United States, Founding Father who served as the third president of the United States from 18 ...
(1743–1826), was among the most influential leaders in early America; during the American Revolutionary War (1775–83), Jefferson served in the Virginia legislature, the Continental Congress, was governor of Virginia, later serving as U.S. minister to France, U.S. secretary of state, vice president under John Adams (1735–1826), writer of the Declaration of Independence and the third U.S. president. During Jefferson's two terms in office (1801–1809), the U.S. purchased the Louisiana Territory and Lewis and Clark explored the vast new acquisition. After leaving office, he retired to his Virginia plantation, Monticello, and helped spearhead the University of Virginia. Jefferson was also a student of
agriculture Agriculture or farming is the practice of cultivating plants and livestock. Agriculture was the key development in the rise of sedentary human civilization, whereby farming of domesticated species created food surpluses that enabled people ...
who introduced various types of rice, olive trees, and grasses into the New World. He stressed the scientific aspect of the
Lewis and Clark Lewis may refer to: Names * Lewis (given name), including a list of people with the given name * Lewis (surname), including a list of people with the surname Music * Lewis (musician), Canadian singer * "Lewis (Mistreated)", a song by Radiohead ...
expedition (1804–06), which explored the
Pacific Northwest The Pacific Northwest (sometimes Cascadia, or simply abbreviated as PNW) is a geographic region in western North America bounded by its coastal waters of the Pacific Ocean to the west and, loosely, by the Rocky Mountains to the east. Thou ...
, and detailed, systematic information on the region's plants and animals was one of that expedition's legacies. Like Franklin and Jefferson, most American scientists of the late 18th century were involved in the struggle to win American independence and forge a new nation. These scientists included the astronomer
David Rittenhouse David Rittenhouse (April 8, 1732 – June 26, 1796) was an American astronomer, inventor, clockmaker, mathematician, surveyor, scientific instrument craftsman, and public official. Rittenhouse was a member of the American Philosophical Society a ...
, the medical scientist
Benjamin Rush Benjamin Rush (April 19, 1813) was a Founding Father of the United States who signed the United States Declaration of Independence, and a civic leader in Philadelphia, where he was a physician, politician, social reformer, humanitarian, educa ...
, and the natural historian
Charles Willson Peale Charles Willson Peale (April 15, 1741 – February 22, 1827) was an American Painting, painter, soldier, scientist, inventor, politician and naturalist. He is best remembered for his portrait paintings of leading figures of the American Revolu ...
. During the American Revolution, Rittenhouse helped design the defenses of
Philadelphia Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Since ...
and built
telescope A telescope is a device used to observe distant objects by their emission, absorption, or reflection of electromagnetic radiation. Originally meaning only an optical instrument using lenses, curved mirrors, or a combination of both to obse ...
s and navigation instruments for the United States' military services. After the war, Rittenhouse designed road and canal systems for the state of
Pennsylvania Pennsylvania (; ( Pennsylvania Dutch: )), officially the Commonwealth of Pennsylvania, is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States. It borders Delaware to its southeast, ...
. He later returned to studying the stars and planets and gained a worldwide reputation in that field. As United States Surgeon General, Benjamin Rush saved countless lives of soldiers during the
American Revolutionary War The American Revolutionary War (April 19, 1775 – September 3, 1783), also known as the Revolutionary War or American War of Independence, was a major war of the American Revolution. Widely considered as the war that secured the independence of t ...
by promoting
hygiene Hygiene is a series of practices performed to preserve health. According to the World Health Organization (WHO), "Hygiene refers to conditions and practices that help to maintain health and prevent the spread of diseases." Personal hygiene refer ...
and
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
practices. By introducing new medical treatments, he made the Pennsylvania Hospital in Philadelphia an example of medical enlightenment, and after his military service, Rush established the first free clinic in the United States. Charles Willson Peale is best remembered as an artist, but he also was a natural historian, inventor, educator, and politician. He created the first major museum in the United States, the
Peale Museum The Peale, located in Baltimore, Maryland, is Baltimore's Community Museum. Its mission is to evolve the role of museums in society by providing local creators and storytellers with the space and support the need to realize a complete and access ...
in Philadelphia, which housed the young nation's only collection of North American natural history specimens. Peale excavated the bones of an ancient
mastodon A mastodon ( 'breast' + 'tooth') is any proboscidean belonging to the extinct genus ''Mammut'' (family Mammutidae). Mastodons inhabited North and Central America during the late Miocene or late Pliocene up to their extinction at the end of the ...
near
West Point, New York West Point is the oldest continuously occupied military post in the United States. Located on the Hudson River in New York, West Point was identified by General George Washington as the most important strategic position in America during the Ame ...
; he spent three months assembling the skeleton, and then displayed it in his museum. The Peale Museum started an American tradition of making the knowledge of science interesting and available to the general public.


Science immigration

American political leaders' enthusiasm for knowledge also helped ensure a warm welcome for scientists from other countries. A notable early immigrant was the British chemist
Joseph Priestley Joseph Priestley (; 24 March 1733 – 6 February 1804) was an English chemist, natural philosopher, separatist theologian, grammarian, multi-subject educator, and liberal political theorist. He published over 150 works, and conducted ...
, who was driven from his homeland because of his dissenting politics. Priestley, who migrated to the United States in 1794, was the first of thousands of talented scientists drawn to the United States in search of a free, creative environment. Other scientists had come to the United States to take part in the nation's rapid growth.
Alexander Graham Bell Alexander Graham Bell (, born Alexander Bell; March 3, 1847 – August 2, 1922) was a Scottish-born inventor, scientist and engineer who is credited with patenting the first practical telephone. He also co-founded the American Telephone and T ...
, who arrived from
Scotland Scotland (, ) is a country that is part of the United Kingdom. Covering the northern third of the island of Great Britain, mainland Scotland has a border with England to the southeast and is otherwise surrounded by the Atlantic Ocean to ...
by way of
Canada Canada is a country in North America. Its ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, covering over , making it the world's second-largest country by to ...
in 1872, developed and patented the
telephone A telephone is a telecommunications device that permits two or more users to conduct a conversation when they are too far apart to be easily heard directly. A telephone converts sound, typically and most efficiently the human voice, into e ...
and related inventions. Charles Proteus Steinmetz, who came from
Germany Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwee ...
in 1889, developed new alternating-current electrical systems at
General Electric Company The General Electric Company (GEC) was a major British industrial conglomerate involved in consumer and defence electronics, communications, and engineering. The company was founded in 1886, was Britain's largest private employer with over 250 ...
, and
Vladimir Zworykin Vladimir Kosma Zworykin; or with the patronymic as ''Kosmich''; or russian: Кузьмич, translit=Kuz'mich, label=none. Zworykin anglicized his name to ''Vladimir Kosma Zworykin'', replacing the patronymic with the name ''Kosma'' as a middle ...
, an immigrant who arrived from
Russia Russia (, , ), or the Russian Federation, is a transcontinental country spanning Eastern Europe and Northern Asia. It is the largest country in the world, with its internationally recognised territory covering , and encompassing one-ei ...
to the States in 1919, bringing his knowledge of x-rays and cathode ray tubes and later won his first patent on a television system he invented. The
Serbia Serbia (, ; Serbian: , , ), officially the Republic of Serbia ( Serbian: , , ), is a landlocked country in Southeastern and Central Europe, situated at the crossroads of the Pannonian Basin and the Balkans. It shares land borders with Hu ...
n
Nikola Tesla Nikola Tesla ( ; ,"Tesla"
''Random House Webster's Unabridged Dictionary''.
; 1856 – 7 January 1943 ...
went to the United States in 1884, and would later adapt the principle of the
rotating magnetic field A rotating magnetic field is the resultant magnetic field produced by a system of coils symmetrically placed and supplied with polyphase currents. A rotating magnetic field can be produced by a poly-phase (two or more phases) current or by a singl ...
in the development of an alternating current
induction motor An induction motor or asynchronous motor is an AC electric motor in which the electric current in the rotor needed to produce torque is obtained by electromagnetic induction from the magnetic field of the stator winding. An induction motor ...
and polyphase system for the generation, transmission, distribution and use of electrical power. Into the early 1900s, Europe remained the center of science research, notably in England and Germany. From the 1920s onwards, the tensions heralding the onset of
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the World War II by country, vast majority of the world's countries—including all of the great power ...
spurred sporadic but steady scientific emigration, or " brain drain", in Europe. Many of these emigrants were Jewish scientists, fearing the repercussions of anti-Semitism, especially in Germany and Italy, and sought sanctuary in the United States. One of the first to do so was
Albert Einstein Albert Einstein ( ; ; 14 March 1879 – 18 April 1955) was a German-born theoretical physicist, widely acknowledged to be one of the greatest and most influential physicists of all time. Einstein is best known for developing the theor ...
in 1933. At his urging, and often with his support, a good percentage of Germany's theoretical physics community, previously the best in the world, left for the United States.
Enrico Fermi Enrico Fermi (; 29 September 1901 – 28 November 1954) was an Italian (later naturalized American) physicist and the creator of the world's first nuclear reactor, the Chicago Pile-1. He has been called the "architect of the nuclear age" an ...
, came from
Italy Italy ( it, Italia ), officially the Italian Republic, ) or the Republic of Italy, is a country in Southern Europe. It is located in the middle of the Mediterranean Sea, and its territory largely coincides with the homonymous geographical ...
in 1938, and led the work that produced the world's first self-sustaining
nuclear chain reaction In nuclear physics, a nuclear chain reaction occurs when one single nuclear reaction causes an average of one or more subsequent nuclear reactions, thus leading to the possibility of a self-propagating series of these reactions. The specific nu ...
. Many other scientists of note moved to the U.S. during this same emigration wave, including Niels Bohr, Victor Weisskopf,
Otto Stern :''Otto Stern was also the pen name of German women's rights activist Louise Otto-Peters (1819–1895)''. Otto Stern (; 17 February 1888 – 17 August 1969) was a German-American physicist and Nobel laureate in physics. He was the second most ...
, and
Eugene Wigner Eugene Paul "E. P." Wigner ( hu, Wigner Jenő Pál, ; November 17, 1902 – January 1, 1995) was a Hungarian-American theoretical physicist who also contributed to mathematical physics. He received the Nobel Prize in Physics in 1963 "for his co ...
. Several scientific and technological breakthroughs during the Atomic Age were the handiwork of such immigrants, who recognized the potential threats and uses of new technology. For instance, it was German professor Einstein and his Hungarian colleague, Leó Szilárd, who took the initiative and convinced President Franklin D. Roosevelt to pursue the pivotal
Manhattan Project The Manhattan Project was a research and development undertaking during World War II that produced the first nuclear weapons. It was led by the United States with the support of the United Kingdom and Canada. From 1942 to 1946, the project w ...
. Many physicists instrumental to the project were also European immigrants, such as the Hungarian Edward Teller, "father of the hydrogen bomb," and German Nobel laureate Hans Bethe. Their scientific contributions, combined with Allied resources and facilities helped establish the United States during World War II as an unrivaled scientific juggernaut. In fact, the Manhattan Project's Operation Alsos and its components, while not designed to recruit European scientists, successfully collected and evaluated Axis military scientific research at the end of the war, especially that of the German nuclear energy project, only to conclude that it was years behind its American counterpart. When World War II ended, the United States, the United Kingdom and the Soviet Union were all intent on capitalizing on Nazi research and competed for the spoils of war. While President Harry S. Truman refused to provide sanctuary to ideologically committed members of the Nazi party, the
Office of Strategic Services The Office of Strategic Services (OSS) was the intelligence agency of the United States during World War II. The OSS was formed as an agency of the Joint Chiefs of Staff (JCS) to coordinate espionage activities behind enemy lines for all branc ...
introduced
Operation Paperclip Operation Paperclip was a secret United States intelligence program in which more than 1,600 German scientists, engineers, and technicians were taken from the former Nazi Germany to the U.S. for government employment after the end of World War ...
, conducted under the Joint Intelligence Objectives Agency. This program covertly offered otherwise ineligible intellectuals and technicians whitewashed dossiers, biographies, and employment. Ex-Nazi scientists overseen by the JIOA had been employed by the U.S. military since the defeat of the Nazi regime in Project Overcast, but Operation Paperclip ventured to systematically allocate German nuclear and aerospace research and scientists to military and civilian posts, beginning in August 1945. Until the program's termination in 1990, Operation Paperclip was said to have recruited over 1,600 such employees in a variety of professions and disciplines. In the first phases of Operation Paperclip, these recruits mostly included aerospace engineers from the German
V-2 The V-2 (german: Vergeltungswaffe 2, lit=Retaliation Weapon 2), with the technical name ''Aggregat 4'' (A-4), was the world’s first long-range guided ballistic missile. The missile, powered by a liquid-propellant rocket engine, was develope ...
combat rocket program, experts in aerospace medicine and synthetic fuels. Perhaps the most influential of these was Wernher Von Braun, who had worked on the
Aggregate Aggregate or aggregates may refer to: Computing and mathematics * collection of objects that are bound together by a root entity, otherwise known as an aggregate root. The aggregate root guarantees the consistency of changes being made within the ...
rockets (the first rocket program to reach outer space), and chief designer of the V-2 rocket program. Upon reaching American soil, Von Braun first worked on the
United States Air Force The United States Air Force (USAF) is the air service branch of the United States Armed Forces, and is one of the eight uniformed services of the United States. Originally created on 1 August 1907, as a part of the United States Army Si ...
ICBM program before his team was reassigned to
NASA The National Aeronautics and Space Administration (NASA ) is an independent agency of the US federal government responsible for the civil space program, aeronautics research, and space research. NASA was established in 1958, succeedin ...
. Often credited as “The Father of Rocket Science,” his work on the Redstone rocket and the successful deployment of the
Explorer 1 Explorer 1 was the first satellite launched by the United States in 1958 and was part of the U.S. participation in the International Geophysical Year (IGY). The mission followed the first two satellites the previous year; the Soviet Union's S ...
satellite as a response to
Sputnik 1 Sputnik 1 (; see § Etymology) was the first artificial Earth satellite. It was launched into an elliptical low Earth orbit by the Soviet Union on 4 October 1957 as part of the Soviet space program. It sent a radio signal back to Earth for ...
marked the beginning of the American Space program, and therefore, of the
Space Race The Space Race was a 20th-century competition between two Cold War rivals, the United States and the Soviet Union, to achieve superior spaceflight capability. It had its origins in the ballistic missile-based nuclear arms race between the t ...
. Von Braun's subsequent development of the
Saturn V Saturn V is a retired American super heavy-lift launch vehicle developed by NASA under the Apollo program for human exploration of the Moon. The rocket was human-rated, with multistage rocket, three stages, and powered with liquid-propellant r ...
rocket for NASA in the mid-to late sixties resulted in the first crewed landing on the Moon, the
Apollo 11 Apollo 11 (July 16–24, 1969) was the American spaceflight that first landed humans on the Moon. Commander Neil Armstrong and lunar module pilot Buzz Aldrin landed the Apollo Lunar Module ''Eagle'' on July 20, 1969, at 20:17 UTC, ...
mission in 1969. In the post-war era, the U.S. was left in a position of unchallenged scientific leadership, being one of the few industrial countries not ravaged by war. Additionally, science and technology were seen to have greatly added to the Allied war victory, and were seen as absolutely crucial in the Cold War era. This enthusiasm simultaneously rejuvenated American industry, and celebrated Yankee ingenuity, instilling a zealous nationwide investment in "Big Science" and state-of-the-art government funded facilities and programs. This state patronage presented appealing careers to the intelligentsia, and further consolidated the scientific preeminence of the United States. As a result, the U.S. government became, for the first time, the largest single supporter of basic and applied scientific research. By the mid-1950s, the research facilities in the U.S. were second to none, and scientists were drawn to the U.S. for this reason alone. The changing pattern can be seen in the winners of the
Nobel Prize in physics ) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then " ...
and chemistry. During the first half-century of Nobel Prizes – from 1901 to 1950 – American winners were in a distinct minority in the science categories. Since 1950, Americans have won approximately half of the Nobel Prizes awarded in the sciences. See the
List of Nobel laureates by country This is a list of Nobel Prize laureates by country. Listings for ''Economics'' refer to the related Nobel Memorial Prize in Economic Sciences. The Nobel Prizes and the Prize in Economic Sciences have been awarded 567 times to 889 recipients, of w ...
. The American Brain Gain continued throughout the
Cold War The Cold War is a term commonly used to refer to a period of geopolitical tension between the United States and the Soviet Union and their respective allies, the Western Bloc and the Eastern Bloc. The term '' cold war'' is used because t ...
, as tensions steadily escalated in the
Eastern Bloc The Eastern Bloc, also known as the Communist Bloc and the Soviet Bloc, was the group of socialist states of Central and Eastern Europe, East Asia, Southeast Asia, Africa, and Latin America under the influence of the Soviet Union that existed du ...
, resulting in a steady trickle of defectors, refugees and emigrants. The partition of Germany, for one, precipitated over three and a half million East Germans – the Republikflüchtling - to cross into West Berlin by 1961. Most of them were young, well-qualified, educated professionals or skilled workers - the intelligentsia - exacerbating human capital flight in the GDR to the benefit of Western countries, including the United States. Technology inflows from abroad have played an important role in the development of the United States, especially in the late nineteenth century. A favorable U.S. security environment that allowed relatively low defense spending. High trade barriers encouraged the development of domestic manufacturing industries and the inflow of foreign technologies.


American applied science

During the 19th century, Britain,
France France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pac ...
, and
Germany Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwee ...
were at the forefront of new ideas in science and mathematics. But if the United States lagged behind in the formulation of theory, it excelled in using theory to solve problems:
applied science Applied science is the use of the scientific method and knowledge obtained via conclusions from the method to attain practical goals. It includes a broad range of disciplines such as engineering and medicine. Applied science is often contrasted ...
. This tradition had been born of necessity. Because Americans lived so far from the well-springs of Western science and manufacturing, they often had to figure out their own ways of doing things. When Americans combined theoretical knowledge with "
Yankee ingenuity Yankee ingenuity is a self-made stereotype of inventiveness, technical solutions to practical problems, "know-how", self-reliance and individual enterprise associated with the Yankees, who originated in New England and developed much of the indust ...
", the result was a flow of important inventions. The great American inventors include
Robert Fulton Robert Fulton (November 14, 1765 – February 24, 1815) was an American engineer and inventor who is widely credited with developing the world's first commercially successful steamboat, the (also known as ''Clermont''). In 1807, that steambo ...
(the
steamboat A steamboat is a boat that is marine propulsion, propelled primarily by marine steam engine, steam power, typically driving propellers or Paddle steamer, paddlewheels. Steamboats sometimes use the ship prefix, prefix designation SS, S.S. or S/S ...
); Samuel Morse (the
telegraph Telegraphy is the long-distance transmission of messages where the sender uses symbolic codes, known to the recipient, rather than a physical exchange of an object bearing the message. Thus flag semaphore is a method of telegraphy, whereas ...
);
Eli Whitney Eli Whitney Jr. (December 8, 1765January 8, 1825) was an American inventor, widely known for inventing the cotton gin, one of the key inventions of the Industrial Revolution that shaped the economy of the Antebellum South. Although Whitney hi ...
(the
cotton gin A cotton gin—meaning "cotton engine"—is a machine that quickly and easily separates cotton fibers from their seeds, enabling much greater productivity than manual cotton separation.. Reprinted by McGraw-Hill, New York and London, 1926 (); a ...
);
Cyrus McCormick Cyrus Hall McCormick (February 15, 1809 – May 13, 1884) was an American inventor and businessman who founded the McCormick Harvesting Machine Company, which later became part of the International Harvester Company in 1902. Originally from the ...
(the reaper); and
Thomas Alva Edison Thomas Alva Edison (February 11, 1847October 18, 1931) was an American inventor and businessman. He developed many devices in fields such as electric power generation, mass communication, sound recording, and motion pictures. These inventi ...
, the most fertile of them all, with more than a thousand inventions credited to his name. Edison was not always the first to devise a scientific application, but he was frequently the one to bring an idea to a practical finish. For example, the British engineer Joseph Swan built an incandescent electric lamp in 1860, almost 20 years before Edison. But Edison's
light bulb An electric light, lamp, or light bulb is an electrical component that produces light. It is the most common form of artificial lighting. Lamps usually have a base made of ceramic, metal, glass, or plastic, which secures the lamp in the soc ...
s lasted much longer than Swan's, and they could be turned on and off individually, while Swan's bulbs could be used only in a system where several lights were turned on or off at the same time. Edison followed up his improvement of the light bulb with the development of electrical generating systems. Within 30 years, his inventions had introduced electric lighting into millions of homes. Another landmark application of scientific ideas to practical uses was the innovation of the brothers Wilbur and Orville Wright. In the 1890s, they became fascinated with accounts of German glider experiments and began their own investigation into the principles of flight. Combining scientific knowledge and mechanical skills, the Wright brothers built and flew several
glider Glider may refer to: Aircraft and transport Aircraft * Glider (aircraft), heavier-than-air aircraft primarily intended for unpowered flight ** Glider (sailplane), a rigid-winged glider aircraft with an undercarriage, used in the sport of gliding ...
s. Then, on December 17, 1903, they successfully flew the first heavier-than-air, mechanically propelled
airplane An airplane or aeroplane (informally plane) is a fixed-wing aircraft that is propelled forward by thrust from a jet engine, propeller, or rocket engine. Airplanes come in a variety of sizes, shapes, and wing configurations. The broad ...
. An American invention that was barely noticed in 1947 went on to usher in the
Information Age The Information Age (also known as the Computer Age, Digital Age, Silicon Age, or New Media Age) is a historical period that began in the mid-20th century. It is characterized by a rapid shift from traditional industries, as established during ...
. In that year
John Bardeen John Bardeen (; May 23, 1908 – January 30, 1991) was an American physicist and engineer. He is the only person to be awarded the Nobel Prize in Physics twice: first in 1956 with William Shockley and Walter Brattain for the invention of the tra ...
,
William Shockley William Bradford Shockley Jr. (February 13, 1910 – August 12, 1989) was an American physicist and inventor. He was the manager of a research group at Bell Labs that included John Bardeen and Walter Brattain. The three scientists were jointl ...
, and Walter Brattain of
Bell Laboratories Nokia Bell Labs, originally named Bell Telephone Laboratories (1925–1984), then AT&T Bell Laboratories (1984–1996) and Bell Labs Innovations (1996–2007), is an American industrial Research and development, research and scientific developm ...
drew upon highly sophisticated principles of
quantum physics Quantum mechanics is a fundamental theory in physics that provides a description of the physical properties of nature at the scale of atoms and subatomic particles. It is the foundation of all quantum physics including quantum chemistry, qua ...
to invent the
transistor upright=1.4, gate (G), body (B), source (S) and drain (D) terminals. The gate is separated from the body by an insulating layer (pink). A transistor is a semiconductor device used to Electronic amplifier, amplify or electronic switch, switch ...
, a small substitute for the bulky
vacuum tube A vacuum tube, electron tube, valve (British usage), or tube (North America), is a device that controls electric current flow in a high vacuum between electrodes to which an electric potential difference has been applied. The type known as ...
. This, and a device invented 10 years later, the
integrated circuit An integrated circuit or monolithic integrated circuit (also referred to as an IC, a chip, or a microchip) is a set of electronic circuits on one small flat piece (or "chip") of semiconductor material, usually silicon. Large numbers of tiny ...
, made it possible to package enormous amounts of electronics into tiny containers. As a result, book-sized computers of today can outperform room-sized computers of the 1960s, and there has been a revolution in the way people live – in how they work, study, conduct business, and engage in research. World War II had a profound impact on the development of science and technology in the United States. Before World War II, the federal government basically did not assume responsibility for supporting scientific development. During the war, the federal government and science formed a new cooperative relationship. After the war, the federal government became the main role in supporting science and technology. And in the following years, the federal government supported the establishment of a national modern science and technology system, making America a world leader in science and technology. Part of America's past and current preeminence in applied science has been due to its vast research and development budget, which at $401.6bn in 2009 was more than double that of China's $154.1bn and over 25% greater than the European Union's $297.9bn.


The Atomic Age and "Big Science"

One of the most spectacular – and controversial – accomplishments of US technology has been the harnessing of nuclear energy. The concepts that led to the splitting of the atom were developed by the scientists of many countries, but the conversion of these ideas into the reality of nuclear fission was accomplished in the United States in the early 1940s, both by many Americans but also aided tremendously by the influx of European intellectuals fleeing the growing conflagration sparked by
Adolf Hitler Adolf Hitler (; 20 April 188930 April 1945) was an Austrian-born German politician who was dictator of Germany from 1933 until his death in 1945. He rose to power as the leader of the Nazi Party, becoming the chancellor in 1933 and the ...
and
Benito Mussolini Benito Amilcare Andrea Mussolini (; 29 July 188328 April 1945) was an Italian politician and journalist who founded and led the National Fascist Party. He was Prime Minister of Italy from the March on Rome in 1922 until his deposition in ...
in Europe. During these crucial years, a number of the most prominent European scientists, especially physicists, immigrated to the United States, where they would do much of their most important work; these included Hans Bethe,
Albert Einstein Albert Einstein ( ; ; 14 March 1879 – 18 April 1955) was a German-born theoretical physicist, widely acknowledged to be one of the greatest and most influential physicists of all time. Einstein is best known for developing the theor ...
,
Enrico Fermi Enrico Fermi (; 29 September 1901 – 28 November 1954) was an Italian (later naturalized American) physicist and the creator of the world's first nuclear reactor, the Chicago Pile-1. He has been called the "architect of the nuclear age" an ...
, Leó Szilárd, Edward Teller, Felix Bloch, Emilio Segrè,
John von Neumann John von Neumann (; hu, Neumann János Lajos, ; December 28, 1903 – February 8, 1957) was a Hungarian-American mathematician, physicist, computer scientist, engineer and polymath. He was regarded as having perhaps the widest c ...
, and
Eugene Wigner Eugene Paul "E. P." Wigner ( hu, Wigner Jenő Pál, ; November 17, 1902 – January 1, 1995) was a Hungarian-American theoretical physicist who also contributed to mathematical physics. He received the Nobel Prize in Physics in 1963 "for his co ...
, among many, many others. American academics worked hard to find positions at laboratories and universities for their European colleagues. After German physicists split a
uranium Uranium is a chemical element with the symbol U and atomic number 92. It is a silvery-grey metal in the actinide series of the periodic table. A uranium atom has 92 protons and 92 electrons, of which 6 are valence electrons. Uranium is weak ...
nucleus Nucleus ( : nuclei) is a Latin word for the seed inside a fruit. It most often refers to: * Atomic nucleus, the very dense central region of an atom *Cell nucleus, a central organelle of a eukaryotic cell, containing most of the cell's DNA Nucl ...
in 1938, a number of scientists concluded that a nuclear chain reaction was feasible and possible. The Einstein–Szilárd letter to President Franklin D. Roosevelt warned that this breakthrough would permit the construction of "extremely powerful bombs." This warning inspired an executive order towards the investigation of using uranium as a weapon, which later was superseded during
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the World War II by country, vast majority of the world's countries—including all of the great power ...
by the
Manhattan Project The Manhattan Project was a research and development undertaking during World War II that produced the first nuclear weapons. It was led by the United States with the support of the United Kingdom and Canada. From 1942 to 1946, the project w ...
the full Allied effort to be the first to build an
atomic bomb A nuclear weapon is an explosive device that derives its destructive force from nuclear reactions, either fission (fission bomb) or a combination of fission and fusion reactions ( thermonuclear bomb), producing a nuclear explosion. Both bomb ...
. The project bore fruit when the first such bomb was exploded in
New Mexico ) , population_demonym = New Mexican ( es, Neomexicano, Neomejicano, Nuevo Mexicano) , seat = Santa Fe, New Mexico, Santa Fe , LargestCity = Albuquerque, New Mexico, Albuquerque , LargestMetro = Albuquerque metropolitan area, Tiguex , Offi ...
on July 16, 1945. The development of the bomb and its use against
Japan Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the n ...
in August 1945 initiated the Atomic Age, a time of anxiety over
weapons of mass destruction A weapon of mass destruction (WMD) is a chemical, biological, radiological, nuclear, or any other weapon that can kill and bring significant harm to numerous individuals or cause great damage to artificial structures (e.g., buildings), natu ...
that has lasted through the Cold War and down to the anti-proliferation efforts of today. Even so, the Atomic Age has also been characterized by peaceful uses of
nuclear power Nuclear power is the use of nuclear reactions to produce electricity. Nuclear power can be obtained from nuclear fission, nuclear decay and nuclear fusion reactions. Presently, the vast majority of electricity from nuclear power is produced b ...
, as in the advances in nuclear power and
nuclear medicine Nuclear medicine or nucleology is a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease. Nuclear imaging, in a sense, is " radiology done inside out" because it records radiation emi ...
. Along with the production of the atomic bomb, World War II also began an era known as " Big Science" with increased government patronage of scientific research. The advantage of a scientifically and technologically sophisticated country became all too apparent during wartime, and in the ideological Cold War to follow the importance of scientific strength in even peacetime applications became too much for the government to any more leave to philanthropy and private industry alone. This increased expenditure on scientific research and education propelled the United States to the forefront of the international scientific community—an amazing feat for a country which only a few decades before still had to send its most promising students to Europe for extensive scientific education. The first US commercial nuclear power plant started operation in
Illinois Illinois ( ) is a state in the Midwestern United States. Its largest metropolitan areas include the Chicago metropolitan area, and the Metro East section, of Greater St. Louis. Other smaller metropolitan areas include, Peoria and Rock ...
in 1956. At the time, the future for nuclear energy in the United States looked bright. But opponents criticized the safety of power plants and questioned whether safe disposal of nuclear waste could be assured. A 1979 accident at Three Mile Island in Pennsylvania turned many Americans against nuclear power. The cost of building a nuclear power plant escalated, and other, more economical sources of power began to look more appealing. During the 1970s and 1980s, plans for several nuclear plants were cancelled, and the future of nuclear power remains in a state of uncertainty in the United States. Meanwhile, American scientists have been experimenting with other
renewable energy Renewable energy is energy that is collected from renewable resources that are naturally replenished on a human timescale. It includes sources such as sunlight, wind, the movement of water, and geothermal heat. Although most renewable energy ...
, including
solar power Solar power is the conversion of energy from sunlight into electricity, either directly using photovoltaics (PV) or indirectly using concentrated solar power. Photovoltaic cells convert light into an electric current using the photovolta ...
. Although solar power generation is still not economical in much of the United States, recent developments might make it more affordable.


Telecom and technology

For the past 80 years, the United States has been integral in fundamental advances in
telecommunications Telecommunication is the transmission of information by various types of technologies over wire, radio, optical, or other electromagnetic systems. It has its origin in the desire of humans for communication over a distance greater than that ...
and technology. For example, AT&T's
Bell Laboratories Nokia Bell Labs, originally named Bell Telephone Laboratories (1925–1984), then AT&T Bell Laboratories (1984–1996) and Bell Labs Innovations (1996–2007), is an American industrial Research and development, research and scientific developm ...
spearheaded the American technological revolution with a series of inventions including the first practical light emitted diode ( LED), the
transistor upright=1.4, gate (G), body (B), source (S) and drain (D) terminals. The gate is separated from the body by an insulating layer (pink). A transistor is a semiconductor device used to Electronic amplifier, amplify or electronic switch, switch ...
, the
C programming language ''The C Programming Language'' (sometimes termed ''K&R'', after its authors' initials) is a computer programming book written by Brian Kernighan and Dennis Ritchie, the latter of whom originally designed and implemented the language, as well a ...
, and the
Unix Unix (; trademarked as UNIX) is a family of multitasking, multiuser computer operating systems that derive from the original AT&T Unix, whose development started in 1969 at the Bell Labs research center by Ken Thompson, Dennis Ritchie, ...
computer operating system.
SRI International SRI International (SRI) is an American nonprofit scientific research institute and organization headquartered in Menlo Park, California. The trustees of Stanford University established SRI in 1946 as a center of innovation to support economic ...
and
Xerox PARC PARC (Palo Alto Research Center; formerly Xerox PARC) is a research and development company in Palo Alto, California. Founded in 1969 by Jacob E. "Jack" Goldman, chief scientist of Xerox Corporation, the company was originally a division of Xero ...
in
Silicon Valley Silicon Valley is a region in Northern California that serves as a global center for high technology and innovation. Located in the southern part of the San Francisco Bay Area, it corresponds roughly to the geographical areas San Mateo Cou ...
helped give birth to the
personal computer A personal computer (PC) is a multi-purpose microcomputer whose size, capabilities, and price make it feasible for individual use. Personal computers are intended to be operated directly by an end user, rather than by a computer expert or te ...
industry, while ARPA and
NASA The National Aeronautics and Space Administration (NASA ) is an independent agency of the US federal government responsible for the civil space program, aeronautics research, and space research. NASA was established in 1958, succeedin ...
funded the development of the
ARPANET The Advanced Research Projects Agency Network (ARPANET) was the first wide-area packet-switched network with distributed control and one of the first networks to implement the TCP/IP protocol suite. Both technologies became the technical fou ...
and the
Internet The Internet (or internet) is the global system of interconnected computer networks that uses the Internet protocol suite (TCP/IP) to communicate between networks and devices. It is a '' network of networks'' that consists of private, p ...
. Herman Hollerith was just a twenty-year-old engineer when he realized the need for a better way for the U.S. government to conduct their Census and then proceeded to develop electromechanical tabulators for that purpose. The net effect of the many changes from the
1880 census The United States census of 1880 conducted by the Census Bureau during June 1880 was the tenth United States census.1880 census The United States census of 1880 conducted by the Census Bureau during June 1880 was the tenth United States census.1890 census The United States census of 1890 was taken beginning June 2, 1890, but most of the 1890 census materials were destroyed in 1921 when a building caught fire and in the subsequent disposal of the remaining damaged records. It determined the reside ...
. That kick started The Tabulating Machine Company. By the 1960s, the company name had been changed to International Business Machines, and IBM dominated business computing. IBM revolutionized the industry by bringing out the first comprehensive family of computers (the
System/360 The IBM System/360 (S/360) is a family of mainframe computer systems that was announced by IBM on April 7, 1964, and delivered between 1965 and 1978. It was the first family of computers designed to cover both commercial and scientific applica ...
). It caused many of their competitors to either merge or go bankrupt, leaving IBM in an even more dominant position. IBM is known for its many inventions like the
floppy disk A floppy disk or floppy diskette (casually referred to as a floppy, or a diskette) is an obsolescent type of disk storage composed of a thin and flexible disk of a magnetic storage medium in a square or nearly square plastic enclosure lined ...
, introduced in 1971, supermarket checkout products, and introduced in 1973, the IBM 3614 Consumer Transaction Facility, an early form of today's Automatic Teller Machines. In 1983, the
DynaTAC 8000x DynaTAC is a series of cellular telephones manufactured by Motorola, Inc. from 1983 to 1994. The Motorola DynaTAC 8000X commercial portable cellular phone received approval from the U.S. FCC on September 21, 1983. A full charge took rough ...
was the first commercially available handheld mobile phone. From 1983 to 2014, worldwide mobile phone subscriptions grew to over seven billion; enough to provide one for every person on Earth.


The Space Age

Running almost in tandem with the Atomic Age has been the
Space Age The Space Age is a period encompassing the activities related to the Space Race, space exploration, space technology, and the cultural developments influenced by these events, beginning with the launch of Sputnik 1 during 1957, and continuing ...
. American Robert Goddard was one of the first scientists to experiment with rocket propulsion systems. In his small laboratory in
Worcester, Massachusetts Worcester ( , ) is a city and county seat of Worcester County, Massachusetts, United States. Named after Worcester, England, the city's population was 206,518 at the 2020 census, making it the second- most populous city in New England after ...
, Goddard worked with
liquid oxygen Liquid oxygen—abbreviated LOx, LOX or Lox in the aerospace, submarine and gas industries—is the liquid form of molecular oxygen. It was used as the oxidizer in the first liquid-fueled rocket invented in 1926 by Robert H. Goddard, an app ...
and
gasoline Gasoline (; ) or petrol (; ) (see ) is a transparent, petroleum-derived flammable liquid that is used primarily as a fuel in most spark-ignited internal combustion engines (also known as petrol engines). It consists mostly of organic c ...
to propel rockets into the
atmosphere An atmosphere () is a layer of gas or layers of gases that envelop a planet, and is held in place by the gravity of the planetary body. A planet retains an atmosphere when the gravity is great and the temperature of the atmosphere is low. A ...
, and in 1926 successfully fired the world's first liquid-fuel rocket which reached a height of 12.5 meters. Over the next 10 years, Goddard's rockets achieved modest altitudes of nearly two kilometers, and interest in rocketry increased in the United States, Britain, Germany, and the Soviet Union. As Allied forces advanced during World War II, both the American and Russian forces searched for top German scientists who could be claimed as spoils for their country. The American effort to bring home German rocket technology in
Operation Paperclip Operation Paperclip was a secret United States intelligence program in which more than 1,600 German scientists, engineers, and technicians were taken from the former Nazi Germany to the U.S. for government employment after the end of World War ...
, and the bringing of German rocket scientist Wernher von Braun (who would later sit at the head of a
NASA The National Aeronautics and Space Administration (NASA ) is an independent agency of the US federal government responsible for the civil space program, aeronautics research, and space research. NASA was established in 1958, succeedin ...
center) stand out in particular. Expendable rockets provided the means for launching artificial
satellite A satellite or artificial satellite is an object intentionally placed into orbit in outer space. Except for passive satellites, most satellites have an electricity generation system for equipment on board, such as solar panels or radioiso ...
s, as well as crewed
spacecraft A spacecraft is a vehicle or machine designed to fly in outer space. A type of artificial satellite, spacecraft are used for a variety of purposes, including communications, Earth observation, meteorology, navigation, space colonization, ...
. In 1957, the
Soviet Union The Soviet Union,. officially the Union of Soviet Socialist Republics. (USSR),. was a transcontinental country that spanned much of Eurasia from 1922 to 1991. A flagship communist state, it was nominally a federal union of fifteen nationa ...
launched the first satellite,
Sputnik 1 Sputnik 1 (; see § Etymology) was the first artificial Earth satellite. It was launched into an elliptical low Earth orbit by the Soviet Union on 4 October 1957 as part of the Soviet space program. It sent a radio signal back to Earth for ...
, and the United States followed with
Explorer 1 Explorer 1 was the first satellite launched by the United States in 1958 and was part of the U.S. participation in the International Geophysical Year (IGY). The mission followed the first two satellites the previous year; the Soviet Union's S ...
in 1958. The first
human spaceflight Human spaceflight (also referred to as manned spaceflight or crewed spaceflight) is spaceflight with a crew or passengers aboard a spacecraft, often with the spacecraft being operated directly by the onboard human crew. Spacecraft can also be ...
s were made in early 1961, first by Soviet cosmonaut
Yuri Gagarin Yuri Alekseyevich Gagarin; Gagarin's first name is sometimes transliterated as ''Yuriy'', ''Youri'', or ''Yury''. (9 March 1934 – 27 March 1968) was a Soviet pilot and cosmonaut who became the first human to journey into outer space. T ...
and then by American astronaut
Alan Shepard Alan Bartlett Shepard Jr. (November 18, 1923 – July 21, 1998) was an American astronaut, naval aviator, test pilot, and businessman. In 1961, he became the second person and the first American to travel into space and, in 1971, he beca ...
. From those first tentative steps, to the
Apollo 11 Apollo 11 (July 16–24, 1969) was the American spaceflight that first landed humans on the Moon. Commander Neil Armstrong and lunar module pilot Buzz Aldrin landed the Apollo Lunar Module ''Eagle'' on July 20, 1969, at 20:17 UTC, ...
landing on the Moon and the partially reusable
Space Shuttle The Space Shuttle is a retired, partially reusable low Earth orbital spacecraft system operated from 1981 to 2011 by the U.S. National Aeronautics and Space Administration (NASA) as part of the Space Shuttle program. Its official program n ...
, the American space program brought forth a breathtaking display of applied science.
Communications satellite A communications satellite is an artificial satellite that relays and amplifies radio telecommunication signals via a transponder; it creates a communication channel between a source transmitter and a receiver at different locations on Earth ...
s transmit computer data, telephone calls, and radio and television broadcasts.
Weather satellite A weather satellite or meteorological satellite is a type of Earth observation satellite that is primarily used to monitor the weather and climate of the Earth. Satellites can be polar orbiting (covering the entire Earth asynchronously), or ...
s furnish the data necessary to provide early warnings of severe storms. Global positioning satellites were first developed in the U.S. starting around 1972, and became fully operational by 1994. Interplanetary probes and space telescopes began a golden age of
planetary science Planetary science (or more rarely, planetology) is the scientific study of planets (including Earth), celestial bodies (such as moons, asteroids, comets) and planetary systems (in particular those of the Solar System) and the processes of their ...
and advanced a wide variety of astronomical work. On April 20, 2021, MOXIE produced oxygen from Martian atmospheric
carbon dioxide Carbon dioxide ( chemical formula ) is a chemical compound made up of molecules that each have one carbon atom covalently double bonded to two oxygen atoms. It is found in the gas state at room temperature. In the air, carbon dioxide is t ...
using solid oxide electrolysis, the first experimental extraction of a
natural resource Natural resources are resources that are drawn from nature and used with few modifications. This includes the sources of valued characteristics such as commercial and industrial use, aesthetic value, scientific interest and cultural value. ...
from another planet for human use. In 2022, the United States ranked 2nd in the
Global Innovation Index The Global Innovation Index is an annual ranking of countries by their capacity for, and success in, innovation, published by the World Intellectual Property Organization. It was started in 2007 by INSEAD and ''World Business'', a British m ...
.


Medicine and health care

As in physics and chemistry, Americans have dominated the Nobel Prize for
physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemic ...
or medicine since World War II. The
private sector The private sector is the part of the economy, sometimes referred to as the citizen sector, which is owned by private groups, usually as a means of establishment for profit or non profit, rather than being owned by the government. Employment The ...
has been the focal point for biomedical research in the United States, and has played a key role in this achievement. As of 2000, for-profit industry funded 57%, non-profit private organizations such as the
Howard Hughes Medical Institute The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fi ...
funded 7%, and the tax-funded
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the lat ...
(NIH) funded 36% of medical research in the United States.The Benefits of Medical Research and the Role of the NIH
However, by 2003, the NIH funded only 28% of medical research funding; funding by private industry increased 102% from 1994 to 2003.Medical Research Spending Doubled Over Past Decade
Neil Osterweil, MedPage Today, September 20, 2005
The NIH consists of 24 separate institutes in
Bethesda, Maryland Bethesda () is an unincorporated, census-designated place in southern Montgomery County, Maryland. It is located just northwest of Washington, D.C. It takes its name from a local church, the Bethesda Meeting House (1820, rebuilt 1849), which ...
. The goal of NIH research is knowledge that helps prevent, detect, diagnose, and treat disease and disability. At any given time, grants from the NIH support the research of about 35,000 principal investigators. Five Nobel Prize-winners have made their prize-winning discoveries in NIH laboratories. NIH research has helped make possible numerous medical achievements. For example, mortality from
heart disease Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, h ...
, the number-one killer in the United States, dropped 41 percent between 1971 and 1991. The death rate for strokes decreased by 59 percent during the same period. Between 1991 and 1995, the cancer death rate fell by nearly 3 percent, the first sustained decline since national record-keeping began in the 1930s. And today more than 70 percent of children who get cancer are cured. With the help of the NIH,
molecular genetics Molecular genetics is a sub-field of biology that addresses how differences in the structures or expression of DNA molecules manifests as variation among organisms. Molecular genetics often applies an "investigative approach" to determine the ...
and
genomics Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...
research have revolutionized biomedical science. In the 1980s and 1990s, researchers performed the first trial of
gene therapy Gene therapy is a Medicine, medical field which focuses on the genetic modification of cells to produce a therapeutic effect or the treatment of disease by repairing or reconstructing defective genetic material. The first attempt at modifying ...
in humans and are now able to locate, identify, and describe the function of many genes in the
human genome The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the ...
. Research conducted by universities, hospitals, and corporations also contributes to improvement in diagnosis and treatment of disease. NIH funded the basic research on Acquired Immune Deficiency Syndrome (
AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ma ...
), for example, but many of the drugs used to treat the disease have emerged from the laboratories of the American pharmaceutical industry; those drugs are being tested in research centers across the country.


See also

* Science policy of the United States * Biomedical research in the United States * Technological and industrial history of the United States *
Timeline of United States inventions The following articles cover the timeline of United States inventions: *Timeline of United States inventions (before 1890), before the turn of the century *Timeline of United States inventions (1890–1945), before World War II *Timeline of Unite ...
*
Timeline of United States discoveries Timeline of United States discoveries encompasses the breakthroughs of human thought and knowledge of new scientific findings, phenomena, places, things, and what was previously unknown to exist. From a historical stand point, the timeline below o ...
*
National Inventors Hall of Fame The National Inventors Hall of Fame (NIHF) is an American not-for-profit organization, founded in 1973, which recognizes individual engineers and inventors who hold a U.S. patent of significant technology. Besides the Hall of Fame, it also oper ...
*
United States Patent and Trademark Office The United States Patent and Trademark Office (USPTO) is an agency in the U.S. Department of Commerce that serves as the national patent office and trademark registration authority for the United States. The USPTO's headquarters are in Alex ...
* NASA spinoff technologies *
Yankee ingenuity Yankee ingenuity is a self-made stereotype of inventiveness, technical solutions to practical problems, "know-how", self-reliance and individual enterprise associated with the Yankees, who originated in New England and developed much of the indust ...


References

{{DEFAULTSORT:Science And Technology In The United States