In 2000, Griffith graduated from the University of Sydney with a Master of Engineering degree. He won a scholarship to MIT Media Lab to study towards a PhD that he completed in 2004. The subject of his PhD thesis was "self-replicating machines". They were one of the first instances of artificial replication being demonstrated using real physics.
Saul is the co-founder and CEO of OtherLab, a research and development company working on computational manufacturing and design tools and applying those tools to projects such as inflatable pneumatic robots and prostheses, novel approaches to heliostat design, and applications of computational origami to the design of pressure vessels (e.g. for compressed natural gas) in arbitrary shapes.
He is married to Tim O'Reilly's daughter Arwen.