Sanjeev Das (born 27 August 1976) is an Indian cancer biologist and a scientist at National Institute of Immunology, New Delhi, India. He is well regarded for his studies on tumor suppressor proteins. He is a recipient of the National Bioscience Award for Career Development of the

Department of Biotechnology The Department of Biotechnology (DBT) is an Indian government department, under the Ministry of Science and Technology responsible for administrating development and commercialisation in the field of modern biology and biotechnology in India. It ...

. The

Council of Scientific and Industrial Research The Council of Scientific and Industrial Research (IAST: ''vaigyanik tathā audyogik anusandhāna pariṣada''), abbreviated as CSIR, was established by the Government of India in September 1942 as an autonomous body that has emerged as the l ...

, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, for his contributions to biological sciences in 2017.

Biography

Sanjeev Das was born on 27 August 1976 to Wg Cdr P K Das (retd) and Gopa Das at Ajmer (Nasirabad Cantt), Rajasthan, India. He earned his master's degree (MSc) from the University College of Science & Technology,

University of Calcutta The University of Calcutta (informally known as Calcutta University; CU) is a Public university, public collegiate university, collegiate State university (India), state university in India, located in Kolkata, West Bengal, India. Considered ...

and continued his studies at the Indian Institute of Science from where he secured a PhD. His post -doctoral studies were in the US, at the Cutaneous Biology Research Center of

Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...

and

Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...

. Returning to India, he joined the

National Institute of Immunology, India National Institute of Immunology (NII) is an autonomous research institute located in New Delhi, under the Department of Biotechnology (DBT) for research in immunology. NII was established on 24 June 1981, with Prof. M. G. K. Menon as Chairman ...

as a faculty where he is a set up the Molecular Oncology Laboratory. Sanjeev is married to Rajashree and has a daughter Mrinalini. The family lives in NII campus in New Delhi.

Legacy

The research of Sanjeev Das has been focusing on the various aspects of cancer biology which is reported to have assisted in widening the understanding of the functioning of P53 and

sirtuins Sirtuins are a family of signaling proteins involved in metabolic regulation. They are ancient in animal evolution and appear to possess a highly conserved structure throughout all kingdoms of life. Chemically, sirtuins are a class of proteins ...

. He is also involved in research on tumor suppressor proteins, tumor cell metabolism and

tumorigenesis Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abno ...

, especially the impact of regulatory networks and metabolic processes. His studies have been documented by way of a number of research articles in peer-reviewed journals.

Awards and honors

Das received the NASI-SCOPUS Young Scientist Award jointly awarded by the

National Academy of Sciences, India The National Academy of Sciences, India, established in 1930, is the oldest science academy in India. It is located in Prayagraj, Uttar Pradesh. Prof. Meghnad Saha was the founder president. Fellows *Suddhasatwa Basu * Sudha Bhattacharya * Ch ...

and

Elsevier Elsevier () is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as ''The Lancet'', ''Cell'', the ScienceDirect collection of electronic journals, '' Trends'', th ...

in 2014 and the

National Bioscience Award for Career Development The National Bio-science Award for Career Development or N-BIOS Prize is an Indian science award for recognizing excellence and promoting research in bio-sciences disciplines. It was instituted in 1999 by the Department of Biotechnology of the Gov ...

of the

in 2015. The Indian Council of Medical Research awarded him the Shakuntala Amir Chand Prize in 2016 and he received the Prof. Umakant Sinha Memorial Award of the

Indian Science Congress Association Indian Science Congress Association(ISCA) is a premier scientific organisation of India with headquarters at Kolkata, West Bengal. The association started in the year 1914 in Kolkata and it meets annually in the first week of January. It has a ...

in 2017. The Council of Scientific and Industrial Research awarded him the

Shanti Swarup Bhatnagar Prize The Shanti Swarup Bhatnagar Prize for Science and Technology (SSB) is a science award in India given annually by the Council of Scientific and Industrial Research (CSIR) for notable and outstanding research, Applied science, applied or Fundamenta ...

, one of the highest Indian science awards the same year. The award orations delivered by him include the 2016 edition of the Prof. B. K. Bachhawat Memorial Young Scientist Lecture of the National Academy of Sciences, India.

Selected bibliography

* 1. Sen N, Satija YK and Das S. PGC-1alpha, a key modulator of p53, promotes cell survival upon metabolic stress (2011). Molecular Cell, ''44'', 621-634. 2. Sen N, Kumari R, Singh MI and Das S^*. HDAC5, a key component in temporal regulation of p53-mediated transactivation in response to genotoxic stress (2013). Molecular Cell, ''52'', 406-420. 3. Bhardwaj A and Das S. SIRT6 deacetylates PKM2 to suppress its nuclear localization and oncogenic functions (2016). Proc Natl Acad Sci USA, ''113'', E538-E547. 4. Satija YK and Das S. Tyr99 phosphorylation determines the regulatory milieu of tumor suppressor p73 (2016). Oncogene, ''35'', 513–527.

Notes

References

External links

* {{DEFAULTSORT:Das, Sanjeev Recipients of the Shanti Swarup Bhatnagar Award in Biological Science Indian immunologists 1976 births Living people Scientists from West Bengal University of Calcutta alumni Indian Institute of Science alumni Massachusetts General Hospital people N-BIOS Prize recipients Harvard Medical School people