Splicing factor, arginine/serine-rich 9, also known as SFRS9, is a human
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
encoding an
SR protein
SR proteins are a conserved family of proteins involved in RNA splicing. SR proteins are named because they contain a protein domain with long repeats of serine and arginine amino acid residues, whose standard abbreviations are "S" and "R" respe ...
involved in splice site selection in
alternative splicing.
Interactions
SFRS9 has been shown to
interact with
Y box binding protein 1 and
NOL3
Nucleolar protein 3 is a protein that in humans is encoded by the ''NOL3'' gene.
Nol3 has been shown to be induced in multiple cancer types and acts as a repressor of apoptosis leading to resistance and proliferation. Paradoxically, loss of Nol3 ...
.
References
Further reading
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