SB-357134 is a drug which is used in scientific research. It acts as a potent, selective and orally active 5-HT₆ receptor antagonist. SB-357134 and other 5-HT₆ antagonists show

nootropic Nootropics ( , or ) (colloquial: smart drugs and cognitive enhancers, similar to adaptogens) are a wide range of natural or synthetic dietary supplement, supplements or drugs and other substances that are claimed to improve cognitive function ...

effects in animal studies, and have been proposed as potential novel treatments for cognitive disorders such as

schizophrenia Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social wit ...

and Alzheimer's disease.

References

5-HT6 antagonists N-(2-methoxyphenyl)piperazines Sulfonamides Bromoarenes Fluoroarenes {{nervous-system-drug-stub