Renal protein reabsorption is the part of
renal physiology that deals with the retrieval of filtered
proteins, preventing them from disappearing from the body through the urine.
Almost all reabsorption takes place in the
proximal tubule. Only ~1%
[ is left in the final urine.
The proteins cross the ]apical membrane
The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment (t ...
by endocytosis
Endocytosis is a cellular process in which substances are brought into the cell. The material to be internalized is surrounded by an area of cell membrane, which then buds off inside the cell to form a vesicle containing the ingested material. E ...
. They are subsequently degraded in lysosomes. The remaining free amino acids are transported across the basolateral membrane Epithelial polarity is one example of the cell polarity that is a fundamental feature of many types of cells. Epithelial cells feature distinct 'apical', 'lateral' and 'basal' plasma membrane domains. Epithelial cells connect to one another via the ...
by amino acid transporters.[
]
Overview table
References
{{renal physiology
Renal physiology