Renal clearance ratio
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The renal clearance ratio or fractional excretion is a relative measure of the speed at which a constituent of
urine Urine is a liquid by-product of metabolism in humans and in many other animals. Urine flows from the kidneys through the ureters to the urinary bladder. Urination results in urine being excretion, excreted from the body through the urethra. Cel ...
passes through the
kidney The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood ...
s. It is defined by following equation: : clearance\ ratio\ of\ X = \frac * X is the
analyte An analyte, component (in clinical chemistry), or chemical species is a substance or chemical constituent that is of interest in an analytical procedure. The purest substances are referred to as analytes, such as 24 karat gold, NaCl, water, etc. ...
substance * Cx is the renal plasma clearance of X * Cin is the renal plasma clearance of
inulin Inulins are a group of naturally occurring polysaccharides produced by many types of plants, industrially most often extracted from chicory. The inulins belong to a class of dietary fibers known as fructans. Inulin is used by some plants as a mea ...
.
Creatinine Creatinine (; ) is a breakdown product of creatine phosphate from muscle and protein metabolism. It is released at a constant rate by the body (depending on muscle mass). Biological relevance Serum creatinine (a blood measurement) is an import ...
is sometimes used instead of inulin as the reference substance.


See also

* Clearance (pharmacology) *
Kt/V In medicine, ''Kt/V'' is a number used to quantify hemodialysis and peritoneal dialysis treatment adequacy. *''K'' – dialyzer clearance of urea *''t'' – dialysis time *''V'' – volume of distribution of urea, approximately equal to patient's ...


References

{{DEFAULTSORT:Renal Clearance Ratio Nephrology