RU-24,969 is a

drug A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via inhala ...

and research chemical widely used in scientific studies. It is a selective

agonist An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ag ...

at the 5-HT_1A and 5-HT_1B receptors, with preference for the latter. As with other 5-HT_1B agonists such as

CP-94,253 CP-94253 is a drug which acts as a potent and selective serotonin 5-HT1B receptor agonist An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cel ...

, RU-24,969 has been found to increase the reinforcing properties of cocaine, suggesting a role for 5-HT_1B receptors in cocaine addiction.

References

5-HT1A agonists 5-HT1B agonists 5-HT7 agonists Phenol ethers Tetrahydropyridines {{nervous-system-drug-stub

See also

References