Quinagolide (, ), sold under the brand name Norprolac, is a
selective dopamine D2 receptor agonist which is used to reduce elevated levels of
prolactin
Prolactin (PRL), also known as lactotropin, is a protein best known for its role in enabling mammals to produce milk. It is influential in over 300 separate processes in various vertebrates, including humans. Prolactin is secreted from the pit ...
(
hyperprolactinemia
Hyperprolactinaemia is the presence of abnormally high levels of prolactin in the blood. Normal levels average to about 13 ng/mL in women, and 5 ng/mL in men, with an upper normal limit of serum prolactin levels being 15-25 ng/mL ...
).
It has also been found to be effective in the treatment of
breast pain.
Chemistry
Quinagolide is a
racemate
In chemistry, a racemic mixture, or racemate (), is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule or salt. Racemic mixtures are rare in nature, but many compounds are produced industrially as racemates. ...
composed of the following two enantiomers:
References
{{Prolactin receptor modulators
Benzoquinolines
D2-receptor agonists
Phenols
Prolactin inhibitors
Sulfamides
Tocolytics