Quazinone (Dozonone) is a
cardiotonic A cardiac stimulant is a substance which acts as a stimulant of the heart – e.g., via positive chronotropic or inotropic action.
Examples of cardiac stimulant drugs are cocaine and methamphetamine
Methamphetamine (contracted from ) is a p ...
and
vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction, ...
drug
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...
which was developed and marketed in the 1980s for the treatment of
heart disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, hea ...
.
It acts as a
selective PDE3 inhibitor
Inhibitor or inhibition may refer to:
In biology
* Enzyme inhibitor, a substance that binds to an enzyme and decreases the enzyme's activity
* Reuptake inhibitor, a substance that increases neurotransmission by blocking the reuptake of a neurotra ...
.
It is no longer available.
See also
*
Phosphodiesterase inhibitor
References
External links
*
{{Cardiac stimulants excluding cardiac glycosides
Chloroarenes
Imidazoquinazolines
Inotropic agents
Lactams
PDE3 inhibitors
Vasodilators