Protein-synthesizing GTPases (, ''elongation factor (EF)'', ''initiation factor (IF)'', ''peptide-release or termination factor'') are enzymes involved in mRNA translation into protein by the ribosome, with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''GTP phosphohydrolase (mRNA-translation-assisting)''.
They usually include
translation initiation factor Initiation factors are proteins that bind to the small subunit of the ribosome during the initiation of translation, a part of protein biosynthesis.
Initiation factors can interact with repressors to slow down or prevent translation. They have the ...
s such as
IF-2 and
translation elongation factor
Elongation factors are a set of proteins that function at the ribosome, during protein synthesis, to facilitate translational elongation from the formation of the first to the last peptide bond of a growing polypeptide. Most common elongat ...
s such as
EF-Tu
EF-Tu (elongation factor thermo unstable) is a prokaryotic elongation factor responsible for catalyzing the binding of an aminoacyl-tRNA (aa-tRNA) to the ribosome. It is a G-protein, and facilitates the selection and binding of an aa-tRNA to t ...
.
References
External links
*
EC 3.6.5
{{3.6-enzyme-stub