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A prolymphocyte is a white blood cell with a certain state of cellular differentiation in lymphocytopoiesis. In the 20th century it was believed that a sequence of general maturation changed cells from
Histology at hematologyatlas.com (found in sixth row)
Lymphocytes {{Developmental-biology-stub
A prolymphocyte is a white blood cell with a certain state of cellular differentiation in lymphocytopoiesis. In the 20th century it was believed that a sequence of general maturation changed cells from lymphoblast
__NOTOC__
A lymphoblast is a modified naive lymphocyte with altered cell morphology. It occurs when the lymphocyte is activated by an antigen (from antigen-presenting cells) and increased in volume by nucleus and cytoplasm growth as well as new mRN ...
s to prolymphocytes and then to lymphocyte
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include natural killer cells (which function in cell-mediated, cytotoxic innate immunity), T cells (for cell-mediated, cytotoxic ad ...
s (the lymphocytic series), with each being a precursor of the last. Today it is believed that the differentiation of cells in the lymphocyte line is not always simply chronologic but rather depends on antigen exposure, such that, for example, lymphocytes can become lymphoblasts.
The size is between 10 and 18 μm.
See also
*Pluripotential hemopoietic stem cell
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells. This process is called haematopoiesis. In vertebrates, the very first definitive HSCs arise from the ventral endothelial wall of the embryonic aorta within t ...
* Prolymphocytic leukemia
References
External links
Histology at hematologyatlas.com (found in sixth row)
Lymphocytes {{Developmental-biology-stub