Primary cutaneous amyloidosis
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Primary cutaneous amyloidosis is a form of
amyloidosis Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs and symptoms associated with amyloidosis. These include fatigue, peripheral edema, weight ...
associated with
oncostatin M receptor Oncostatin-M specific receptor subunit beta also known as the Oncostatin M receptor (OSMR) , is one of the receptor proteins for oncostatin M, that in humans is encoded by the ''OSMR'' gene. OSMR is a member of the type I cytokine receptor famil ...
. This type of amyloidosis has been divided into the following types: * Macular amyloidosis is a cutaneous condition characterized by itchy, brown, rippled macules usually located on the interscapular region of the back. Combined cases of lichen and macular amyloidosis are termed biphasic amyloidosis, and provide support to the theory that these two variants of amyloidosis exist on the same disease spectrum.Lichen amyloidosis of the auricular concha
Craig, E. (2006) Dermatology Online Journal 12 (5): 1, University of California, Davis Department of Dermatology * Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, typically appearing bilaterally on the shins. File:Histopathology of lichen amyloidosis with Congo red.jpg, Histopathology of lichen amyloidosis, with subepithelial Congo red-positive deposits File:Lichen amyloidosis on leg 1.jpg, Lichen amyloidosis on a 56-year-old male's leg File:Lichen amyloidosis on leg 2.jpg, Lichen amyloidosis on a 56-year-old male's leg * Nodular amyloidosis is a rare cutaneous condition characterized by nodules that involve the acral areas.


See also

*
Amyloidosis Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs and symptoms associated with amyloidosis. These include fatigue, peripheral edema, weight ...
*
List of cutaneous conditions Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ...


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External links

Amyloidosis Skin conditions resulting from errors in metabolism {{Cutaneous-condition-stub