Pregnanetriol, or 5β-pregnane-3α,17α,20α-triol, is a

steroid A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and ...

and inactive

metabolite In biochemistry, a metabolite is an intermediate or end product of metabolism. The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, ...

progesterone Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens and is the majo ...

Urine testing

Urine excretion of pregnanetriol can be measured over a period of 24 hours. Elevated urine pregnanetriol levels suggest adrenogenital syndrome. In monitoring treatment with

cortisol replacement Addison's disease, also known as primary adrenal insufficiency, is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal ...

, elevated urine pregnanetriol levels indicate insufficient dosage of cortisol.online-family-doctor.com Pregnanetriol
Retrieved April 2011

Reference ranges

For females: * 0 to 5 years: < 0.1 mg/24 hours * 6 to 9 years: < 0.3 mg/24 hours * 10 to 15 years: 0.1 to 0.6 mg/24 hours * 16 years and older: 0 to 1.4 mg/ 24 hours. For males: * 0 to 5 years: < 0.1 mg/24 hours * 6 to 9 years: < 0.3 mg/24 hours * 10 to 15 years: 0.2 to 0.6 mg/24 hours * 16 years and older: 0.2 to 2 mg/ 24 hours

References

5β-Pregnanes Human metabolites {{Biochemistry-stub

Urine testing

Reference ranges

See also

References