Photostimulated luminescence
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Photostimulated luminescence (PSL) is the release of stored energy within a
phosphor A phosphor is a substance that exhibits the phenomenon of luminescence; it emits light when exposed to some type of radiant energy. The term is used both for fluorescent or phosphorescent substances which glow on exposure to ultraviolet or v ...
by stimulation with visible light, to produce a luminescent signal.
X-ray An X-ray, or, much less commonly, X-radiation, is a penetrating form of high-energy electromagnetic radiation. Most X-rays have a wavelength ranging from 10 picometers to 10  nanometers, corresponding to frequencies in the range 30&nb ...
s may induce such an energy storage. A plate based on this mechanism is called a photostimulable phosphor (PSP) plate and is one type of
X-ray detector X-ray detectors are devices used to measure the flux, spatial distribution, spectrum, and/or other properties of X-rays. Detectors can be divided into two major categories: imaging detectors (such as photographic plates and X-ray film (photograp ...
used in
projectional radiography Projectional radiography, also known as conventional radiography, is a form of radiography and medical imaging that produces two-dimensional images by x-ray radiation. The image acquisition is generally performed by radiographers, and the images a ...
. Creating an image requires illuminating the plate twice: the first exposure, to the
radiation In physics, radiation is the emission or transmission of energy in the form of waves or particles through space or through a material medium. This includes: * ''electromagnetic radiation'', such as radio waves, microwaves, infrared, visi ...
of interest, "writes" the image, and a later, second illumination (typically by a visible-wavelength
laser A laser is a device that emits light through a process of optical amplification based on the stimulated emission of electromagnetic radiation. The word "laser" is an acronym for "light amplification by stimulated emission of radiation". The ...
) "reads" the image. The device to read such a plate is known as a phosphorimager (occasionally spelled phosphoimager, perhaps reflecting its common application in
molecular biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and phys ...
for detecting radiolabeled phosphorylated
proteins Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
and
nucleic acids Nucleic acids are biopolymers, macromolecules, essential to all known forms of life. They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous base. The two main cl ...
).
Projectional radiography Projectional radiography, also known as conventional radiography, is a form of radiography and medical imaging that produces two-dimensional images by x-ray radiation. The image acquisition is generally performed by radiographers, and the images a ...
using a photostimulable phosphor plate as an
X-ray detector X-ray detectors are devices used to measure the flux, spatial distribution, spectrum, and/or other properties of X-rays. Detectors can be divided into two major categories: imaging detectors (such as photographic plates and X-ray film (photograp ...
can be called "phosphor plate radiography" or "computed radiography" (not to be confused with computed tomography which uses computer processing to convert multiple projectional radiographies to a
3D image Stereoscopy (also called stereoscopics, or stereo imaging) is a technique for creating or enhancing the illusion of depth in an image by means of stereopsis for binocular vision. The word ''stereoscopy'' derives . Any stereoscopic image is ...
).


Structure and mechanism


Energy storage

On photostimulable phosphor (PSP) plates, the phosphor layer is typically 0.1 to 0.3 mm thick. After the initial exposure by short-
wavelength In physics, the wavelength is the spatial period of a periodic wave—the distance over which the wave's shape repeats. It is the distance between consecutive corresponding points of the same phase on the wave, such as two adjacent crests, tr ...
(typically,
X-ray An X-ray, or, much less commonly, X-radiation, is a penetrating form of high-energy electromagnetic radiation. Most X-rays have a wavelength ranging from 10 picometers to 10  nanometers, corresponding to frequencies in the range 30&nb ...
)
electromagnetic radiation In physics, electromagnetic radiation (EMR) consists of waves of the electromagnetic (EM) field, which propagate through space and carry momentum and electromagnetic radiant energy. It includes radio waves, microwaves, infrared, (visib ...
, excited electrons in the
phosphor A phosphor is a substance that exhibits the phenomenon of luminescence; it emits light when exposed to some type of radiant energy. The term is used both for fluorescent or phosphorescent substances which glow on exposure to ultraviolet or v ...
material remain 'trapped' in 'colour centres' ("F-centers") in the
crystal A crystal or crystalline solid is a solid material whose constituents (such as atoms, molecules, or ions) are arranged in a highly ordered microscopic structure, forming a crystal lattice that extends in all directions. In addition, macro ...
lattice until stimulated by the second illumination. For example, Fuji's photostimulable phosphor is deposited on a flexible polyester film support with grain size about 5 micrometers, and is described as " barium fluorobromide containing a trace amount of bivalent
europium Europium is a chemical element with the symbol Eu and atomic number 63. Europium is the most reactive lanthanide by far, having to be stored under an inert fluid to protect it from atmospheric oxygen or moisture. Europium is also the softest lan ...
as a luminescence center". Europium is a divalent cation that replaces barium to create a
solid solution A solid solution, a term popularly used for metals, is a homogenous mixture of two different kinds of atoms in solid state and have a single crystal structure. Many examples can be found in metallurgy, geology, and solid-state chemistry. The wor ...
. When Eu2+ ions are struck by ionizing radiation, they lose an additional electron to become Eu3+ ions. These electrons enter the
conduction band In solid-state physics, the valence band and conduction band are the bands closest to the Fermi level, and thus determine the electrical conductivity of the solid. In nonmetals, the valence band is the highest range of electron energies in ...
of the crystal and become trapped in the bromine ion empty lattice of the crystal, resulting in a
metastable state In chemistry and physics, metastability denotes an intermediate energetic state within a dynamical system other than the system's state of least energy. A ball resting in a hollow on a slope is a simple example of metastability. If the ball ...
that is higher in energy than the original condition.


Energy release and digitalization

A lower-frequency light source that is insufficient in energy to create more Eu3+ ions can return the trapped electrons to the conduction band. As these mobilized electrons encounter Eu3+ ions, they release a blue-violet 400 nm luminescence. This light is produced in proportion to the number of trapped electrons, and thus in proportion to the original X-ray signal. It can be collected often by a
photomultiplier tube Photomultiplier tubes (photomultipliers or PMTs for short) are extremely sensitive detectors of light in the ultraviolet, visible, and near-infrared ranges of the electromagnetic spectrum. They are members of the class of vacuum tubes, more speci ...
, which is clocked at a specific resolution or pixel capture frequency. The light is thereby converted to an electronic signal and significantly amplified. The electronic signal is then quantized via an ADC to discrete (digital) values for each pixel and placed into the image processor pixel map.


Reuse

Afterwards, the plates can be "erased," by exposing the plate to room-intensity
white light White is the lightest color and is achromatic (having no hue). It is the color of objects such as snow, chalk, and milk, and is the opposite of black. White objects fully reflect and scatter all the visible wavelengths of light. White on ...
. Thereby, the plate can be used over and over again. Imaging plates can theoretically be re-used thousands of times if they are handled carefully and under certain radiation exposure conditions. PSP plate handling under industrial conditions often results in damage after a few hundred uses. Mechanical damage such as scratches and abrasions are common, as well as radiation fatigue or imprinting due to high energy applications. An image can be erased by simply exposing the plate to a room-level fluorescent light - but more efficient, complete erasure is required to avoid signal carry-over and artifacts. Most laser scanners automatically erase the plate (current technology uses red LED lighting) after laser scanning is complete. The imaging plate can then be re-used. Reusable phosphor plates are environmentally safe but need to be disposed of according to local regulations due to the composition of the phosphor, which contains the heavy metal Barium.


Uses

Computed radiography is used for both
industrial radiography Industrial radiography is a modality of non-destructive testing that uses ionizing radiation to inspect materials and components with the objective of locating and quantifying defects and degradation in material properties that would lead to the ...
and medical
projectional radiography Projectional radiography, also known as conventional radiography, is a form of radiography and medical imaging that produces two-dimensional images by x-ray radiation. The image acquisition is generally performed by radiographers, and the images a ...
. Image plate detectors have also been used in numerous
crystallography Crystallography is the experimental science of determining the arrangement of atoms in crystalline solids. Crystallography is a fundamental subject in the fields of materials science and solid-state physics ( condensed matter physics). The wor ...
studies.


Medical X-ray Imaging

In phosphor plate radiography, the imaging plate is housed in a special cassette and placed under the body part or object to be examined and the x-ray exposure is made. The imaging plate is then run through a special laser scanner, or CR reader, that reads and converts the image to a digital radiograph. The digital image can then be viewed and enhanced using software that has functions very similar to other conventional digital image-processing software, such as contrast, brightness, filtration and zoom. CR imaging plates (IPs) can be retrofitted to existing exam rooms and used in multiple x-ray sites since IPs are processed through a CR reader (scanner) that can be shared between multiple exam rooms.


Differences from Direct Radiography

PSP plate radiography is often distinguished from Direct Radiography (DR). Direct radiography usually refers to image capture onto an amorphous silicon or selenium flat panel detector (FPD), the data being directly passed electronically to the processing computer. PSP plate radiography instead uses a cassette containing the imaging plate, which stores the image until it is read out and loaded into the computer. This additional extra step, from exposing the detector to a viewable digital image, is the main difference between the two techniques. PSP plates and DR FPDs are typically used for
projectional radiography Projectional radiography, also known as conventional radiography, is a form of radiography and medical imaging that produces two-dimensional images by x-ray radiation. The image acquisition is generally performed by radiographers, and the images a ...
. This should not be confused with
fluoroscopy Fluoroscopy () is an imaging technique that uses X-rays to obtain real-time moving images of the interior of an object. In its primary application of medical imaging, a fluoroscope () allows a physician to see the internal structure and function ...
, where there is a continuous beam of radiation and the images appear on the screen in real time, for which PSP plates cannot be used.


History

Image plates were pioneered for commercial medical use by
Fuji Fuji may refer to: Places China * Fuji, Xiangcheng City (付集镇), town in Xiangcheng City, Henan Japan * Mount Fuji, the tallest mountain in Japan * Fuji River * Fuji, Saga, town in Saga Prefecture * Fuji, Shizuoka, city in Shizuoka Prefec ...
in the 1980s.


See also

*
X-ray image intensifier An X-ray image intensifier (XRII) is an image intensifier that converts X-rays into visible light at higher intensity than the more traditional fluorescent screens can. Such intensifiers are used in X-ray imaging systems (such as fluoroscopes) ...
* Radioluminescence * Spinthariscope *
Fluoroscopy Fluoroscopy () is an imaging technique that uses X-rays to obtain real-time moving images of the interior of an object. In its primary application of medical imaging, a fluoroscope () allows a physician to see the internal structure and function ...
* Digital radiography


References

{{reflist X-rays Radiography Nondestructive testing