Phosphoserine transaminase (, ''PSAT'', ''phosphoserine aminotransferase'', ''3-phosphoserine aminotransferase'', ''hydroxypyruvic phosphate-glutamic transaminase'', ''L-phosphoserine aminotransferase'', ''phosphohydroxypyruvate transaminase'', ''phosphohydroxypyruvic-glutamic transaminase'', ''3-O-phospho-L-serine:2-oxoglutarate aminotransferase'', ''SerC'', ''PdxC'', ''3PHP transaminase'') is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''O-phospho-L-serine:2-oxoglutarate aminotransferase''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking ...
: (1) O-phospho-L-serine + 2-
oxoglutarate Ketoglutaric acid or oxoglutaric acid, or its conjugate base, the carboxylate ketoglutarate or oxoglutarate, may refer to the following chemical compounds:
* α-Ketoglutaric acid, an intermediate in the citric acid cycle
The citric acid cycle (CA ...
3-phosphonooxypyruvate + L-
glutamate
Glutamic acid (symbol Glu or E; the ionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins. It is a non-essential nutrient for humans, meaning that the human body can synt ...
: (2) 4-phosphonooxy-L-threonine + 2-oxoglutarate
(3R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + L-glutamate
This enzyme is a pyridoxal-phosphate protein.
See also
*
PSAT1
Phosphoserine aminotransferase (PSA) also known as phosphohydroxythreonine aminotransferase (PSAT) is an enzyme that in humans is encoded by the ''PSAT1'' gene.
The protein encoded by this gene is likely a phosphoserine aminotransferase, based o ...
References
External links
*
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EC 2.6.1