Philip Handler
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Philip Handler (August 13, 1917 – December 29, 1981) was an American
nutritionist A nutritionist is a person who advises others on matters of food and nutrition and their impacts on health. Some people specialize in particular areas, such as sports nutrition, public health, or animal nutrition, among other disciplines. In many c ...
, and biochemist. He was President of the
United States National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
for two terms from 1969 to 1981. He was also a recipient of the
National Medal of Science The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral and social scienc ...
.


Biography

Handler grew up in a Jewish family in New York City. He received his B.S. degree from the
City College of New York The City College of the City University of New York (also known as the City College of New York, or simply City College or CCNY) is a public university within the City University of New York (CUNY) system in New York City. Founded in 1847, Cit ...
in 1936 and his Ph.D. from
University of Illinois The University of Illinois Urbana-Champaign (U of I, Illinois, University of Illinois, or UIUC) is a public land-grant research university in Illinois in the twin cities of Champaign and Urbana. It is the flagship institution of the University ...
in 1939. He taught at
Duke University Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James ...
where he was named the youngest chairman of the Department of Biochemistry, at 35. Handler remained at Duke until 1969, when he accepted the position of president of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
. As a biochemist, he published more than 200 papers on nutrition and metabolic activity. He was elected to the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
in 1964. He received the
National Medal of Science The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral and social scienc ...
in 1981 for "his outstanding contribution to biochemical research, resulting in significant contributions to mankind, including research which led to a clearer understanding of
pellagra Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B3). Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. Areas of the skin exposed to either sunlight or friction are typically affected first. Over t ...
" (Bioscience Article). His research led to the first understanding of nicotinic acid deficiency and the discovery of the tryptophan-nicotinic acid relationship. Handler also provided an understanding of the oxidation of
sarcosine Sarcosine, also known as ''N''-methylglycine, or monomethylglycine, is a monopeptide with the formula CH3N(H)CH2CO2H. It exists at neutral pH as the zwitterion CH3N+(H)2CH2CO2−, which can be obtained as a white, water-soluble powder. Like some ...
to
glycine Glycine (symbol Gly or G; ) is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid (carbamic acid is unstable), with the chemical formula NH2‐ CH2‐ COOH. Glycine is one of the proteinogeni ...
and
formaldehyde Formaldehyde ( , ) (systematic name methanal) is a naturally occurring organic compound with the formula and structure . The pure compound is a pungent, colourless gas that polymerises spontaneously into paraformaldehyde (refer to section F ...
, which led to the importance of single-carbon atoms in metabolism. His final work showed that
methionine Methionine (symbol Met or M) () is an essential amino acid in humans. As the precursor of other amino acids such as cysteine and taurine, versatile compounds such as SAM-e, and the important antioxidant glutathione, methionine plays a critical ro ...
is the only
methyl In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula . In formulas, the group is often abbreviated as Me. This hydrocarbon group occurs in many ...
donor in mammalian metabolism and that there is no pool of methyl groups. As President of the National Academy of Sciences, Handler was instrumental in opening a dialog on American-Soviet cooperation in outer space with his counterpart at the
Soviet Academy of Sciences The Academy of Sciences of the Soviet Union was the highest scientific institution of the Soviet Union from 1925 to 1991, uniting the country's leading scientists, subordinated directly to the Council of Ministers of the Soviet Union (until 1946 ...
in 1970. The discussions would ultimately lead to a joint spaceflight in 1975, the Apollo-Soyuz Test Project. Handler was also responsible for perhaps one of the most notable statues relating to science in the United States: that of
Albert Einstein Albert Einstein ( ; ; 14 March 1879 – 18 April 1955) was a German-born theoretical physicist, widely acknowledged to be one of the greatest and most influential physicists of all time. Einstein is best known for developing the theory ...
at the grounds of the National Academy of Sciences in Washington, DC. Handler was also involved in the creation of the US Department of Health, Education and Welfare (HEW), the predecessor to the
US Department of Health and Human Services The United States Department of Health and Human Services (HHS) is a cabinet-level executive branch department of the U.S. federal government created to protect the health of all Americans and providing essential human services. Its motto is " ...
. Within HEW, Handler had a significant impact on the creation of a multitude of centers within the
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
. He spurred in part by a growing interest in the biosciences, his position on various governmental committees, and the book ''
Biology & The Future of Man Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary in ...
'', which read like a blueprint for a generation of work in the life sciences. Rather abruptly, Handler died in Boston on of pneumonia, after prolonged suffering from lymphoma, just short of six months after leaving office at the Academy. He never returned to Duke University, as he had planned, and never left the hospital after his admission for a thorough checkup in August 1981. He chose for his ashes to be placed alongside those of his colleagues at Duke University Medical Center, where he had started his academic research career.


Positions held


Employment

*1937–1939 Junior Chemist, U. S. Regional Soybean Byproducts Laboratory *Duke University School of Medicine: **1939–1942 Fellow and Instructor, Nutrition and Physiology **1942–1945 Assistant Professor of Physiology **1945–1950 Associate Professor of Biochemistry **1950–1961 Professor of Biochemistry and Chairman of the Department **1961–1969 James B. Duke Professor of Biochemistry (on leave 1969–1981) and Chairman of the Department **1969–1981 President, National Academy of Sciences **1970–1981 Distinguished Professor of Medical Sciences, George Washington University


Public Service

Governmental Positions *1952–1962 Consultant, Veteran's Administration *1964–1968
President's Science Advisory Committee The President's Science Advisory Committee (PSAC) was created on November 21, 1957, by President of the United States Dwight D. Eisenhower, as a direct response to the Soviet launching of the Sputnik 1 and Sputnik 2 satellites. PSAC was an upgrade ...
*1968–1974
President's Science Advisory Committee The President's Science Advisory Committee (PSAC) was created on November 21, 1957, by President of the United States Dwight D. Eisenhower, as a direct response to the Soviet launching of the Sputnik 1 and Sputnik 2 satellites. PSAC was an upgrade ...
*1969–1981 Committee on National Medal of Science *1980 Chairman, U. S. Delegation to the Scientific Forum of the Conference on Security and Cooperation in Europe, Hamburg *National Institutes of Health: **1953–1956 Biochemistry Study Section **1956–1958 Chairman, Biochemistry Study Section **1956–1959 Committee on Health Sciences Training **1958–1961 National Advisory Health Council **1963–1967 National Advisory Council on Research Resources and Facilities *National Science Foundation: **1958–1960 Panel on Biological Research Facilities **1960–1962 Divisional Committee for Biology and Medicine **1962–1974
National Science Board The National Science Board (NSB) of the United States establishes the policies of the National Science Foundation (NSF) within the framework of applicable national policies set forth by the President and the Congress. The NSB also serves as an ind ...
, Member **1964–1966
National Science Board The National Science Board (NSB) of the United States establishes the policies of the National Science Foundation (NSF) within the framework of applicable national policies set forth by the President and the Congress. The NSB also serves as an ind ...
, Vice-Chairman **1966–1970
National Science Board The National Science Board (NSB) of the United States establishes the policies of the National Science Foundation (NSF) within the framework of applicable national policies set forth by the President and the Congress. The NSB also serves as an ind ...
, Chairman Non-Government *1953–1965 Federation of American Societies for Experimental Biology, Member of Board (1953–1965); Executive Committee (1959–1965); Chairman (1964–1965) *1953–1968 American Society of Biological Chemists, Secretary (1953–1958); Councillor (1958–1961); President-elect (1961); President (1962); Chairman, Publications Committee (1965–1968) *1967–1981
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
, Chairman, Committee on the Life Sciences (1967–1970); Councillor (1966–1969); President (1969–1981) *1969–1981 Board of Trustees,
Rockefeller University The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...
*1973–1979 Board of Trustees, Nutrition Foundation *1974–1981 Board of Governors,
Hebrew University of Jerusalem The Hebrew University of Jerusalem (HUJI; he, הַאוּנִיבֶרְסִיטָה הַעִבְרִית בִּירוּשָׁלַיִם) is a public research university based in Jerusalem, Israel. Co-founded by Albert Einstein and Dr. Chaim Weiz ...
*1981 Board of Governors,
Weizmann Institute of Science The Weizmann Institute of Science ( he, מכון ויצמן למדע ''Machon Vaitzman LeMada'') is a public research university in Rehovot, Israel, established in 1934, 14 years before the State of Israel. It differs from other Israeli unive ...


Honors

*Twenty-Eight Honorary Doctorates including: City University of New York (1970), University of North Carolina at Chapel Hill (1971), University of Connecticut (1971), Temple University (1972), George Washington University (1973), Michigan State University (1975), University of Alaska (1977), Ohio State University (1978), University of Illinois (1979), University of Maryland (1979), University of Florida (1979), Medical University of South Carolina (1980), Washington University in St. Louis (1980). *1943 C.B. Mayer Award, New York Academy of Medicine *1964 Member,
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
*1964 Townsend Harris Medal,
City College of New York The City College of the City University of New York (also known as the City College of New York, or simply City College or CCNY) is a public university within the City University of New York (CUNY) system in New York City. Founded in 1847, Cit ...
*1966 Annual Orator, Harvey Gushing Society *1966 Fellow,
American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and ...
*1966 Sigma Xi National Lecturer *1969 Annual Award for Distinguished Contributions to Medical Sciences,
American Medical Association The American Medical Association (AMA) is a professional association and lobbying group of physicians and medical students. Founded in 1847, it is headquartered in Chicago, Illinois. Membership was approximately 240,000 in 2016. The AMA's state ...
*1969 Member,
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
*1970 Benjamin Franklin Fellow, Royal Society for the Encouragement of Arts, Manufacture and Commerce *1970 Honorary Member,
Swiss Academy of Natural Sciences The Swiss Academy of Sciences (SCNAT) is a Switzerland, Swiss national association founded in 1815.Mission
*1972 Alumni Achievement Award,
University of Illinois The University of Illinois Urbana-Champaign (U of I, Illinois, University of Illinois, or UIUC) is a public land-grant research university in Illinois in the twin cities of Champaign and Urbana. It is the flagship institution of the University ...
*1972 German Academy of Natural Sciences, Leopoldina *1973 Honorary Member,
American Institute of Chemists The American Institute of Chemists (AIC) is an organization founded in 1923 with the goal of advancing the chemistry profession in the United States. The institute is known for its yearly awards recognizing contributions of individuals in this fie ...
*1974 Honorary Member,
National Academy of Medicine of Mexico National may refer to: Common uses * Nation or country ** Nationality – a ''national'' is a person who is subject to a nation, regardless of whether the person has full rights as a citizen Places in the United States * National, Maryland, ce ...
*1975 Copernicus Medal,
Polish Academy of Sciences The Polish Academy of Sciences ( pl, Polska Akademia Nauk, PAN) is a Polish state-sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading the development of science across the country by a society of ...
*1977 The Great Cross of Honor with Star, Government of Austria *1977 Insignia of Commander of the Order of Leopold II, King of Belgium *1978 Honorary Member, Imperial Iranian Academy of Sciences *1978 Commander, Order of Merit, People's Republic of Poland *1979 Distinguished Public Service Award, National Science Foundation *1981
National Medal of Science The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral and social scienc ...


Selected quotes

Many of the quotes were found in the Memorial Program honoring his life and held at the National Academy of Sciences.Memorial Service Program handed out at the National Academy of Sciences. Washington, D.C. February 8, 1982 "I am committed to defense of the human rights of all persons, but those of scientists in particular. Not so much because humanity may be denied the fruits of their science, but because they are precious as human beings; because abrogation of their rights is injurious to all mankind; because, as thoughtful intellectuals, scientists not infrequently become involved in the defense of the human rights of others..." – "Science in a Free Society" The
Phi Beta Kappa The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal a ...
Bicentennial Lecture. College of William and Mary. December 6, 1976 "Creative scientific research is one of the very purposes of our society akin to imaginative scholarship in the humanities and innovation in the arts. Surely, no other course available to this civilization is as hopeful as the continuing subtle interplay of science and developing technology." From "The University in a World in Transition." The Convocation Address at the One Hundred and Fiftieth Anniversary of the University of Virginia. October 21, 1969. "Do not fear change – help to guide it. Every technology since fire and the wheel confronted humanity simultaneously with the prospect of great benefit – and of considerable hazard, with potential for good and for evil." From "Science in a Free Society" A Commencement Ceremony Address. Southwestern at Memphis. May 30, 1977.


References

*Jukes, Thomas. "Philip Handler Biographical Sketch" http://jn.nutrition.org/cgi/reprint/113/6/1085 *In Memoriam, Bioscience *National Academy Memorials. Philip Handler. http://www.nap.edu/html/biomems/phandler.pdf


External links


"Philip Handler 1917-1981: A Biographical Memoir"
by Emil L. Smith and Robert L. Hill. National Academy of Sciences, 1985.

{{DEFAULTSORT:Handler, Philip 1917 births 1981 deaths Members of the United States National Academy of Sciences Presidents of the United States National Academy of Sciences American biochemists Jewish American scientists National Medal of Science laureates American nutritionists 20th-century American Jews