Phenoxypropazine (trade name Drazine) is an
irreversible and non-
selective monoamine oxidase inhibitor (MAOI) of the
hydrazine family. It was introduced as an
antidepressant in 1961, but was subsequently withdrawn in 1966 due to
hepatotoxicity
Hepatotoxicity (from ''hepatic toxicity'') implies chemical-driven liver damage. Drug-induced liver injury is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn fr ...
concerns.
See also
*
Hydrazine (antidepressant)
The hydrazine antidepressants are a group of non-selective, irreversible monoamine oxidase inhibitors (MAOIs) which were discovered and initially marketed in the 1950s and 1960s. Most have been withdrawn due to toxicity, namely hepatotoxicity, ...
References
Hepatotoxins
Hydrazines
Monoamine oxidase inhibitors
Phenol ethers
Withdrawn drugs
{{nervous-system-drug-stub