Perdur Radhakantha Adiga
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Perdur Radhakantha Adiga (5 May 1935 – 13 September 2006) was an Indian endocrine biochemist, reproductive biologist, INSA Senior Scientist and an Astra chair professor of the Indian Institute of Science. He was known for his researches on vitamin-carrier proteins and '' Lathyrus sativus'' and was an elected fellow of the Indian Academy of Sciences and the Indian National Science Academy. The
Council of Scientific and Industrial Research The Council of Scientific and Industrial Research (IAST: ''vaigyanik tathā audyogik anusandhāna pariṣada''), abbreviated as CSIR, was established by the Government of India in September 1942 as an autonomous body that has emerged as the l ...
, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 1980.


Biography

P. R. Adiga, born on 5 May 1935 at Barkur, a small hamlet in
Udupi district Udupi district (also Udipi or Odipu in Tulu language) is an administrative subdivision in the Karnataka state of India, with the district headquarters in the city of Udupi. It is situated in the Canara coastal region, there are seven taluks, ...
of the south Indian state of
Karnataka Karnataka (; ISO: , , also known as Karunāḍu) is a state in the southwestern region of India. It was formed on 1 November 1956, with the passage of the States Reorganisation Act. Originally known as Mysore State , it was renamed ''Karnat ...
as one among the ten children of his parents, did his early schooling at local schools and earned a master's degree in biochemistry from the University of Kerala in the neighboring state. Subsequently, he joined the Indian Institute of Science as a research associate and pursued his doctoral studies under the guidance of P. S. Sarma, who headed the department of biochemistry, to secure the degree in 1963. He spent his entire career at IISc, holding various positions as that of an assistant professor, associate professor and professor. He also chaired the erstwhile ''Centre for Reproductive Biology and Molecular Endocrinology'' at the institute. Post retirement, he continued his association with IISc as an INSA Senior scientist. Adiga's early researches were focused on the growth and intermediary metabolism of fungi and insects and how they were impacted by the trace elements and metal toxicity. His work on '' Lathyrus sativus'', commonly known as grass pea, revealed that N-oxalyl-diaminopropionic acid, a neurotoxin present in the plant caused the neurological disorder of neurolathyrism in humans. He was also credited with the discovery of
Homoarginine Homoarginine is an nonproteinogenic alpha-amino acid. It is structurally equivalent to a one-methylene group-higher homolog In biology, homology is similarity due to shared ancestry between a pair of structures or genes in different taxa. A ...
, an
amino acid Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha am ...
derivative, found in ''Lathyrus sativus''. Later, he worked on vitamin-carrying proteins which demonstrated how the proteins carried vitamins such as thiamin and
riboflavin Riboflavin, also known as vitamin B2, is a vitamin found in food and sold as a dietary supplement. It is essential to the formation of two major coenzymes, flavin mononucleotide and flavin adenine dinucleotide. These coenzymes are involved in ...
to the foetus and his experiments on rodents showed antibodies generated during pregnancy might cause its termination. He documented his researches by way of several articles in peer-reviewed journals and the online article repository of the Indian Academy of Sciences has listed 192 of them. He edited the book, ''Perspectives in Primate Reproductive Biology'' and contributed chapters to many books published by others; his work has been cited by a number of authors and researchers. He was also associated with two journals, ''
Journal of Biosciences The ''Journal of Biosciences'' is a peer-reviewed scientific journal published by the Indian Academy of Sciences, Bengaluru, India. The current editor-in-chief is Prof. B J Rao (IISER Tirupati, Tirupati). According to the ''Journal Citation Rep ...
'' and ''
Molecular and Cellular Endocrinology ''Molecular and Cellular Endocrinology'' is a peer-reviewed academic journal of endocrinology established in 1974. The journal is published by Elsevier Elsevier () is a Dutch academic publishing company specializing in scientific, technical, ...
'' as a member of their editorial boards. Adiga died on 13 September 2006, at the age of 71, survived by his wife and two daughters.


Awards and honors

Adiga won the Giri Memorial Medal of the Indian Institute of Science in 1963, for his PhD thesis. The
Council of Scientific and Industrial Research The Council of Scientific and Industrial Research (IAST: ''vaigyanik tathā audyogik anusandhāna pariṣada''), abbreviated as CSIR, was established by the Government of India in September 1942 as an autonomous body that has emerged as the l ...
awarded him
Shanti Swarup Bhatnagar Prize The Shanti Swarup Bhatnagar Prize for Science and Technology (SSB) is a science award in India given annually by the Council of Scientific and Industrial Research (CSIR) for notable and outstanding research, Applied science, applied or Fundamenta ...
, one of the highest Indian science awards, in 1980. Two years later, he received the Sanjay Gandhi Award for Science and Technology, the same year that he was elected as a fellow to the Indian Academy of Sciences. The Society of Biological Chemists (India) awarded him the Professor M. Srinivasayya Award in 1984 and the Indian National Science Academy elected him as a fellow the same year. His award orations include the Professor M. R. N. Prasad Memorial lecture of the Indian National Science Academy in 1992.


Selected bibliography


Chapters

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Articles

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See also

*
Nuggehalli Raghuveer Moudgal Nuggehalli Raghuveer Moudgal (4 March 1931 – 8 May 2011) was an Indian reproductive biologist, endocrinologist and the chairman of the Department of Biochemistry and dean of Faculty of Science at the Indian Institute of Science. He was know ...


Notes


References


External links

* {{DEFAULTSORT:Adiga, Perdur Radhakantha Recipients of the Shanti Swarup Bhatnagar Award in Medical Science Indian medical writers 1935 births 2006 deaths Indian biochemists University of Kerala alumni Indian Institute of Science alumni Academic staff of the Indian Institute of Science People from Udupi district Fellows of the Indian Academy of Sciences Fellows of the Indian National Science Academy 20th-century Indian chemists