Per-Ingvar Brånemark
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Per-Ingvar Brånemark (May 3, 1929 – December 20, 2014) was a
Swedish Swedish or ' may refer to: Anything from or related to Sweden, a country in Northern Europe. Or, specifically: * Swedish language, a North Germanic language spoken primarily in Sweden and Finland ** Swedish alphabet, the official alphabet used by ...
physician and research professor, acknowledged as the "father of modern
dental implant A dental implant (also known as an endosseous implant or fixture) is a prosthesis that interfaces with the bone of the jaw or skull to support a dental prosthesis such as a crown, bridge, denture, or facial prosthesis or to act as an orthodonti ...
ology". The ''Brånemark
Osseointegration Osseointegration (from Latin ''osseus'' " bony" and ''integrare'' "to make whole") is the direct structural and functional connection between living bone and the surface of a load-bearing artificial implant ("load-bearing" as defined by Albrekt ...
Center'' (BOC), named after its founder, was founded in 1989 in
Gothenburg Gothenburg (; abbreviated Gbg; sv, Göteborg ) is the second-largest city in Sweden, fifth-largest in the Nordic countries, and capital of the Västra Götaland County. It is situated by the Kattegat, on the west coast of Sweden, and has ...
, Sweden.


Biography

After studying at
Lund University , motto = Ad utrumque , mottoeng = Prepared for both , established = , type = Public research university , budget = SEK 9 billion Anatomy Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its ...
at
Gothenburg University The University of Gothenburg ( sv, Göteborgs universitet) is a university in Sweden's second largest city, Gothenburg. Founded in 1891, the university is the third-oldest of the current Swedish universities and with 37,000 students and 6000 s ...
in 1969. Brånemark has been awarded many prizes for his work, including the coveted Swedish Society of Medicine's Soederberg Prize in 1992—often referred to as the 'mini- Nobel'—and the Swedish Engineering Academy's equally prestigious medal for technical innovation. Brånemark has also been honored with the Harvard School of Dental Medicine Medal for his work on
dental implant A dental implant (also known as an endosseous implant or fixture) is a prosthesis that interfaces with the bone of the jaw or skull to support a dental prosthesis such as a crown, bridge, denture, or facial prosthesis or to act as an orthodonti ...
s in the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
and holds more than 30 honorary positions throughout
Europe Europe is a large peninsula conventionally considered a continent in its own right because of its great physical size and the weight of its history and traditions. Europe is also considered a Continent#Subcontinents, subcontinent of Eurasia ...
and
North America North America is a continent in the Northern Hemisphere and almost entirely within the Western Hemisphere. It is bordered to the north by the Arctic Ocean, to the east by the Atlantic Ocean, to the southeast by South America and the Car ...
, including the Honorary Fellowship of the
Royal Society of Medicine The Royal Society of Medicine (RSM) is a medical society in the United Kingdom, headquartered in London. History The Society was established in 1805 as Medical and Chirurgical Society of London, meeting in two rooms in barristers’ chambers ...
in the UK. In 2003, he received an
honorary doctorate An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or ''ad hon ...
from the
European University of Madrid European University of Madrid (''Universidad Europea de Madrid'' in Spanish language, UEM) is a private university in Madrid, Spain. History Founded in 1995, the school was purchased in 1999 by Sylvan Learning Systems, Inc. In 2004, Sylvan L ...
. He was the winner of the
European Inventor Award The European Inventor Award(formerly European Inventor of the Year Award, renamed in 2010), are presented annually by the European Patent Office, sometimes supported by the respective Presidency of the Council of the European Union and by the Eur ...
2011 in the category Lifetime achievement. In 2014, he died at the age of 85.


Dental implantology

In 1978, the first
Dental Implant A dental implant (also known as an endosseous implant or fixture) is a prosthesis that interfaces with the bone of the jaw or skull to support a dental prosthesis such as a crown, bridge, denture, or facial prosthesis or to act as an orthodonti ...
Consensus Conference was held, sponsored jointly by the
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
and
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
. It was a landmark event, at which
retrospective A retrospective (from Latin ''retrospectare'', "look back"), generally, is a look back at events that took place, or works that were produced, in the past. As a noun, ''retrospective'' has specific meanings in medicine, software development, popu ...
data on
dental implant A dental implant (also known as an endosseous implant or fixture) is a prosthesis that interfaces with the bone of the jaw or skull to support a dental prosthesis such as a crown, bridge, denture, or facial prosthesis or to act as an orthodonti ...
s were collected and analyzed and criteria and standards for implant dentistry were established. In 1982 in
Toronto Toronto ( ; or ) is the capital city of the Canadian province of Ontario. With a recorded population of 2,794,356 in 2021, it is the most populous city in Canada and the fourth most populous city in North America. The city is the ancho ...
, Brånemark presented work that had begun 15 years earlier in Gothenburg. Brånemark's investigations into the phenomenon of
osseointegration Osseointegration (from Latin ''osseus'' " bony" and ''integrare'' "to make whole") is the direct structural and functional connection between living bone and the surface of a load-bearing artificial implant ("load-bearing" as defined by Albrekt ...
, or the biological fusion of
bone A bone is a Stiffness, rigid Organ (biology), organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red blood cell, red and white blood cells, store minerals, provid ...
to a foreign material, reinvigorated the field of implantology. The Toronto conference brought widespread recognition to the Brånemark implant methods and materials and is one of the most significant scientific breakthroughs in
dentistry Dentistry, also known as dental medicine and oral medicine, is the branch of medicine focused on the teeth, gums, and mouth. It consists of the study, diagnosis, prevention, management, and treatment of diseases, disorders, and conditions o ...
since the late 1970s. The Brånemark System of dental implants was bought out and is currently available from
Nobel Biocare Nobel Biocare is a company that manufactures dental implants and CAD/CAM-based individualized prosthetics and is headquartered in Kloten, Switzerland near the Zürich Airport. Nobel Biocare in its current form was founded in 2002. It originates ...
.


Work on osseointegration

Brånemark's work in the field of
osseointegration Osseointegration (from Latin ''osseus'' " bony" and ''integrare'' "to make whole") is the direct structural and functional connection between living bone and the surface of a load-bearing artificial implant ("load-bearing" as defined by Albrekt ...
reinvigorated the realm of implant dentistry and brought it from being a shunned field into one that became recognized and incorporated into dental school curricula and training programs.Shulman, LB; Driskell, TD: Dental Implants: A Historical Perspective. In Block, M; Kent, J; Guerra, L, editors: ''Implants in Dentistry''. Philadelphia: W.B. Saunders, 1997. page 6. Early modern dental implant technology consisted of blade and transosteal implants. Blade implants, introduced in 1967, consisted of a metal blade that was placed within a bony incision that subsequently healed over the horizontally situated piece of metal but allowed a vertical segment to perforate the healed surface. Transosteal implants, the application of which was strictly limited to the
mandible In anatomy, the mandible, lower jaw or jawbone is the largest, strongest and lowest bone in the human facial skeleton. It forms the lower jaw and holds the lower tooth, teeth in place. The mandible sits beneath the maxilla. It is the only movabl ...
, consisted of a number of screws which were inserted into the inferior aspect of the mandible, some of which extended through and through into the oral cavity.Shulman, LB; Driskell, TD: Dental Implants: A Historical Perspective. In Block, M; Kent, J; Guerra, L, editors: ''Implants in Dentistry''. Philadelphia: W.B. Saunders, 1997. page 6 It was previously thought that both of these implant types relied on mechanical retention, as it was heretofore unknown that metal could be fused into the bone. With the advent of our current understanding of
osseointegration Osseointegration (from Latin ''osseus'' " bony" and ''integrare'' "to make whole") is the direct structural and functional connection between living bone and the surface of a load-bearing artificial implant ("load-bearing" as defined by Albrekt ...
however, rootform endosteal implants became the new standard in implant technology. The phenomenon of osseointegration was first described by Bothe et al. in 1940 and later by Leventhal et al. in 1951. Brånemark's studies, and his subsequent coining of the phrase osseointegration, occurred a year after Leventhal during vital
microscopy Microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye (objects that are not within the resolution range of the normal eye). There are three well-known branches of micr ...
studies in
rabbit Rabbits, also known as bunnies or bunny rabbits, are small mammals in the family Leporidae (which also contains the hares) of the order Lagomorpha (which also contains the pikas). ''Oryctolagus cuniculus'' includes the European rabbit speci ...
s using titanium optic chambers. He and his team found that
titanium Titanium is a chemical element with the symbol Ti and atomic number 22. Found in nature only as an oxide, it can be reduced to produce a lustrous transition metal with a silver color, low density, and high strength, resistant to corrosion in ...
ocular Eyes are organs of the visual system. They provide living organisms with vision, the ability to receive and process visual detail, as well as enabling several photo response functions that are independent of vision. Eyes detect light and con ...
s placed into the lower leg bones of rabbits could not be removed from the bones after a period of healing (see photo at right). He then developed and tested a type of dental implant utilizing pure titanium screws, which he termed ''fixtures''. Although the field of implantology was eschewed by dental academia until that time, the "extensive and weighty documentation of implant efficacy and safety" and "early replication by reliable, independent researchers" resulted in the widespread embrace of implantology by the dental community. Brånemark's son, Rickard, has taken this success and is developing orthopedic
prostheses In medicine, a prosthesis (plural: prostheses; from grc, πρόσθεσις, prósthesis, addition, application, attachment), or a prosthetic implant, is an artificial device that replaces a missing body part, which may be lost through trau ...
in the form of artificial arms and legs anchored to the human skeleton. Gösta Larsson (1931–2006) was the first recipient ever of a modern
dental implant A dental implant (also known as an endosseous implant or fixture) is a prosthesis that interfaces with the bone of the jaw or skull to support a dental prosthesis such as a crown, bridge, denture, or facial prosthesis or to act as an orthodonti ...
, which occurred in 1965. Prof. Per-Ingvar Brånemark, by then Professor of Anatomy at
Gothenburg University The University of Gothenburg ( sv, Göteborgs universitet) is a university in Sweden's second largest city, Gothenburg. Founded in 1891, the university is the third-oldest of the current Swedish universities and with 37,000 students and 6000 s ...
in Sweden, placed the first
titanium Titanium is a chemical element with the symbol Ti and atomic number 22. Found in nature only as an oxide, it can be reduced to produce a lustrous transition metal with a silver color, low density, and high strength, resistant to corrosion in ...
dental implant into a human volunteer. Larsson, a Swede who was
edentulous Toothlessness, or edentulism, is the condition of having no teeth. In organisms that naturally have teeth, it is the result of tooth loss. Organisms that never possessed teeth can also be described as edentulous. Examples are the members of the ...
at the time and had been born with severe chin and jaw deformities, agreed to the test because he wanted to have teeth again. He died in 2006, having used his implants for over 40 years.The History Of Dental Implantation
, implantru.com, accessed 2010-06-13


See also

* Osseoincorporation *
Dental Implant A dental implant (also known as an endosseous implant or fixture) is a prosthesis that interfaces with the bone of the jaw or skull to support a dental prosthesis such as a crown, bridge, denture, or facial prosthesis or to act as an orthodonti ...
s *
Osseointegration Osseointegration (from Latin ''osseus'' " bony" and ''integrare'' "to make whole") is the direct structural and functional connection between living bone and the surface of a load-bearing artificial implant ("load-bearing" as defined by Albrekt ...


References


External links


Nobel Biocare Convention 2007Bacterial Persistence in Dentoalveolar Bone Following Extraction: A Microbiological Study and Implications for Dental Implant Treatment - Clinical Implant Dentistry and Related Research
{{DEFAULTSORT:Branemark, Per-Ingvar 1929 births 2014 deaths Dental materials Academic staff of the University of Gothenburg European Inventor Award winners