Pentedrone (also known as α-methylaminovalerophenone) is a
stimulant of the
cathinone class that has been sold as a
designer drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. D ...
and has been found since 2010 as an ingredient in a number of "
bath salt" mixes sold as legal highs.
Pharmacology
Pentedrone acts as a
norepinephrine-dopamine reuptake inhibitor without causing their
release
Release may refer to:
* Art release, the public distribution of an artistic production, such as a film, album, or song
* Legal release, a legal instrument
* News release, a communication directed at the news media
* Release (ISUP), a code to iden ...
, the same mechanism of action as
methylphenidate
Methylphenidate, sold under the brand names Ritalin and Concerta among others, is the most widely prescribed central nervous system (CNS) stimulant medication used to treat attention deficit hyperactivity disorder (ADHD) and, to a lesser exten ...
.
Side effects
Pentedrone has been linked to at least one death where it was combined with
α-PVP and caused heart failure.
Detection
A forensic standard of Pentedrone is available, and the compound has been posted on the Forendex website of potential drugs of abuse.
Legal status
On January 28, 2014, the DEA listed it, along with nine other synthetic cathinones, on the Schedule 1 with a temporary ban, effective February 27, 2014.
Pentedrone is an
Anlage II
Anlage may refer to:
* Allele, a specific version of a gene, as used by Gregor Mendel
* Anlage Süd
''Anlage Süd'' (English: ''Installation South'') was a pair of railway headquarters built for Adolf Hitler in the Nazi-occupied part of southe ...
controlled drug in Germany.
As of October 2015 Pentedrone is a controlled substance in China.
Pentedrone is banned in the Czech Republic.
See also
*
4-Methylpentedrone
4-Methylpentedrone (also known as 4-MPD and 4-Methyl-α-methylamino-valerophenone), is a stimulant drug of the cathinone class that has been sold online as a designer drug. It is a higher homolog of 4-methylmethcathinone (mephedrone) and 4-methy ...
*
Buphedrone
Buphedrone, also known as α-methylamino-butyrophenone (MABP), is a stimulant of the phenethylamine and cathinone chemical classes that was first synthesized in 1928. It is legal in most countries as a research chemical, as long as it is no ...
*
MDPV
Methylenedioxypyrovalerone (MDPV) is a stimulant of the cathinone class that acts as a norepinephrine–dopamine reuptake inhibitor (NDRI). It was first developed in the 1960s by a team at Boehringer Ingelheim. Its activity at the dopamine tra ...
*
Methcathinone
Methcathinone (α-methylamino- propiophenone or ephedrone) (sometimes called "cat" or "jeff" or "catnip" or "M-Kat" or "kat" or "intash" ) is a monoamine alkaloid and psychoactive stimulant, a substituted cathinone. It is used as a recreationa ...
*
Pentylone
*
Substituted cathinone
References
Cathinones
Designer drugs
Norepinephrine–dopamine reuptake inhibitors
{{nervous-system-drug-stub