Padmanabhan Balaram is an Indian

biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...

and a former director of the

Indian Institute of Science The Indian Institute of Science (IISc) is a public, deemed, research university for higher education and research in science, engineering, design, and management. It is located in Bengaluru, in the Indian state of Karnataka. The institute wa ...

Bangalore Bangalore (), officially Bengaluru (), is the capital and largest city of the Indian state of Karnataka. It has a population of more than and a metropolitan population of around , making it the third most populous city and fifth most ...

India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...

. He is a recipient of the third highest Indian civilian honour of

Padma Bhushan The Padma Bhushan is the third-highest civilian award in the Republic of India, preceded by the Bharat Ratna and the Padma Vibhushan and followed by the Padma Shri. Instituted on 2 January 1954, the award is given for "distinguished service ...

(2014) as well as the

TWAS Prize This is a list of recipients of the TWAS Prize, awarded annually by The World Academy of Sciences (TWAS). Summary Agricultural Sciences Biology Chemistry Earth Sciences Engineering Sciences Mathematics Medical Sc ...

(1994). He has been conferred the 2021 R. Bruce Merrifield Award by the American Peptide Society.

Education

Balaram received his bachelor's degree in Chemistry from

Fergusson College Fergusson College is an autonomous public-private college offering various courses in the streams of arts and science in the city of Pune, India. It was founded in 1885 by the Deccan Education Society. Professor Vaman Shivram Apte was its fir ...

University of Pune Savitribai Phule Pune University (SPPU), formerly the University of Poona, is a collegiate public state university located in the city of Pune, India. It was established in 1949, and is spread over a campus in the neighbourhood of Ganeshk ...

followed by a

master's degree A master's degree (from Latin ) is an academic degree awarded by universities or colleges upon completion of a course of study demonstrating mastery or a high-order overview of a specific field of study or area of professional practice.

from the

Indian Institute of Technology, Kanpur The Indian Institute of Technology Kanpur (IIT Kanpur) Hindi: भारतीय प्रौद्योगिकी संस्थान कानपुर) is a public institute of technology located in Kanpur, Uttar Pradesh, India. It was ...

and his PhD degree from

Carnegie Mellon University Carnegie Mellon University (CMU) is a private research university in Pittsburgh, Pennsylvania. One of its predecessors was established in 1900 by Andrew Carnegie as the Carnegie Technical Schools; it became the Carnegie Institute of Technology ...

with Aksel A. Bothner-By. After a postdoctoral stint at

Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...

with Nobel laureate

Robert Burns Woodward Robert Burns Woodward (April 10, 1917 – July 8, 1979) was an American organic chemist. He is considered by many to be the most preeminent synthetic organic chemist of the twentieth century, having made many key contributions to the subject, e ...

, he returned to the Indian Institute of Science, where he has been ever since as a faculty member in the Molecular Biophysics Unit. He presently holds a Chaired Professorship at the National Center for Biological Sciences, Bangalore. During his PhD, Balaram studied the use of negative

Nuclear Overhauser effect The nuclear Overhauser effect (NOE) is the transfer of nuclear spin polarization from one population of spin-active nuclei (e.g. 1H, 13C, 15N etc.) to another via cross-relaxation. A phenomenological definition of the NOE in nuclear magnetic res ...

signals as probes of macromolecular conformations. As a postdoc with Woodword, Balaram worked on the synthesis of the antibiotic

erythromycin Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections, chlamydia infections, pelvic inflammatory disease, and syphilis. It may also be used duri ...

.Prof. P. Balaram lab Webpage at IISc
Retrieved 16 July 2012

Research

Balaram's main area of research has been the investigation of the structure, conformation, and biological activity of designed and natural peptides. To do this, he has extensively used techniques such as

Nuclear Magnetic Resonance Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a ...

spectroscopy,

Infrared Infrared (IR), sometimes called infrared light, is electromagnetic radiation (EMR) with wavelengths longer than those of visible light. It is therefore invisible to the human eye. IR is generally understood to encompass wavelengths from around ...

spectroscopy, and Circular Dichroism, along with

X-ray crystallography X-ray crystallography is the experimental science determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract into many specific directions. By measuring the angles ...

. He has been a major contributor to the evaluation of factors influencing the folding and conformations of designed peptides, and has investigated structural elements playing a key role in the formation of secondary structural motifs such as helices, beta turns, and sheets. Along with

Isabella Karle Isabella Karle (December 2, 1921 – October 3, 2017) was an American chemist who was instrumental in developing techniques to extract plutonium chloride from a mixture containing plutonium oxide. For her scientific work, Karle received the Garva ...

, a frequent collaborator, he has also pioneered the use of alpha-amino isobutyric acid to induce and retain helicity and constrain peptide conformations. Balaram has authored more than 400 research papers, and is a fellow of the

Indian National Science Academy The Indian National Science Academy (INSA) is a national academy in New Delhi for Indian scientists in all branches of science and technology. In August 2019, Dr. Chandrima Shaha was appointed as the president of Indian National Science Academ ...

.National Knowledge Commission member P. Balaram
Retrieved 16 July 2012 He was the editor of the journal ''

Current Science ''Current Science'' is an English-language peer-reviewed multidisciplinary scientific journal. It was established in 1932 and is published by the Current Science Association along with the Indian Academy of Sciences. According to the ''Journal C ...

'' until June 2013.

References

External links

Prof. Padmanabhan Balaram takes charge as new director of IIScIIT Kanpur Alumni Page
{{DEFAULTSORT:Balaram, Padmanabhan Recipients of the Padma Shri in science & engineering Living people Harvard University people Carnegie Mellon University alumni IIT Kanpur alumni Savitribai Phule Pune University alumni Directors of the Indian Institute of Science Year of birth missing (living people) Fellows of the Indian National Science Academy Fellows of the Indian Academy of Sciences Recipients of the Padma Bhushan in science & engineering Scientists from Bangalore Indian biochemists Indian Institute of Science faculty 20th-century Indian chemists 21st-century Indian chemists TWAS laureates Recipients of the Rajyotsava Award 2008