HOME
        TheInfoList






NM_002636
NM_024165

NM_009343
NM_001302397

RefSeq (protein)

NP_002627
NP_077084

NP_001289326
NP_033369

Location (UCSC) Chr 6: 33.41 – 33.42 Mb Chr 17: 26.93 – 26.94 Mb PubMed search [3] [4] Wikidata
View/Edit Human View/Edit Mouse

PHD finger protein 1 is a protein that in humans is encoded by the PHF1 gene.[5][6][7]

Function

This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.[7]

References

  1. ^ a b c ENSG00000225553, ENSG00000239756 GRCh38: Ensembl release 89: ENSG00000112511, ENSG00000225553, ENSG00000239756 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024193 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Coulson M, Robert S, Eyre HJ, Saint R (March 1998). "The identification and localization of a human gene with sequence similarity to Polycomblike of Drosophila melanogaster". Genomics. 48 (3): 381–3. doi:10.1006/geno.1997.5201. PMID 9545646. 
  6. ^ Hong Z, Jiang J, Lan L, Nakajima S, Kanno S, Koseki H, Yasui A (May 2008). "A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell". Nucleic Acids Research. 36 (9): 2939–47. doi:10.1093/nar/gkn146. PMC 2396414Freely accessible. PMID 18385154. 
  7. ^ a b "Entrez Gene: PHF1 PHD finger protein 1". 

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.