P. Roy Vagelos
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Pindaros Roy Vagelos (born October 8, 1929, in Westfield,
New Jersey New Jersey is a state in the Mid-Atlantic and Northeastern regions of the United States. It is bordered on the north and east by the state of New York; on the east, southeast, and south by the Atlantic Ocean; on the west by the Delawa ...
), better known as P. Roy Vagelos or Roy Vagelos, is an American physician and business executive, who was president and chief executive officer (1985) and chairman (1986) of the American pharmaceutical company Merck & Co. (known as MSD outside the U.S.). Since 1995, Vagelos has served as chairman of the board of
Regeneron Pharmaceuticals Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. The company was founded in 1988. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to ...
. He was founding chair of the Prix Galien USA awards committee (from 2007 to 2017) and was the first recipient of the Galien Foundation's Pro Bono Humanum Award, which in 2018 was renamed in his honor to the Roy Vagelos Pro Bono Humanum Award for Global Health Equity. In addition to his business accomplishments, Vagelos is the author of more than 100 scientific papers. He is also on the board of trustees of the
University of Pennsylvania The University of Pennsylvania (also known as Penn or UPenn) is a Private university, private research university in Philadelphia. It is the fourth-oldest institution of higher education in the United States and is ranked among the highest- ...
and has funded three of the university's elite undergraduate programs: The Vagelos Scholars Program in Molecular Life Sciences (MLS), The Vagelos Program in Life Sciences and Management (LSM) and The Vagelos Integrated Program in Energy Research (VIPER).


Biography

Vagelos grew up during the Depression as a son of
Greek Greek may refer to: Greece Anything of, from, or related to Greece, a country in Southern Europe: *Greeks, an ethnic group. *Greek language, a branch of the Indo-European language family. **Proto-Greek language, the assumed last common ancestor ...
immigrants. He attended Rahway High School in his hometown of
Rahway, New Jersey Rahway () is a city in southern Union County, in the U.S. state of New Jersey. A bedroom community of New York City, it is centrally located in the Rahway Valley region, in the New York metropolitan area. The city is southwest of Manhattan ...
. After winning a partial scholarship, he left his family's small restaurant in Rahway, to become a doctor. He majored in chemistry at the
University of Pennsylvania The University of Pennsylvania (also known as Penn or UPenn) is a Private university, private research university in Philadelphia. It is the fourth-oldest institution of higher education in the United States and is ranked among the highest- ...
, graduating
Phi Beta Kappa The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal ...
in 1950. Vagelos later earned an M.D. from
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
in 1954. Vagelos deferred military service while in medical school, but he was obligated to serve a two-year stint as an Army doctor. As a
Columbia University College of Physicians and Surgeons Columbia University Vagelos College of Physicians and Surgeons (VP&S) is the graduate medical school of Columbia University, located at the Columbia University Irving Medical Center in the Washington Heights neighborhood of Manhattan. Founded ...
trained physician, Vagelos obtained a two-year assignment as a scientist at the
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the lat ...
(1956–1966). For Vagelos, it was a fateful turning point. He was associated with
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...
, Washington University and the
Washington University School of Medicine Washington University School of Medicine (WUSM) is the medical school of Washington University in St. Louis in St. Louis, Missouri. Founded in 1891, the School of Medicine has 1,260 students, 604 of which are pursuing a medical degree with ...
(1966–1975) before joining Merck, Sharp & Dohme Research Laboratories in Rahway. He was promoted to CEO and Chairman in 1985 and 1986, respectively, succeeding John J. Horan. He retired from Merck in 1994. The author of more than 100 scientific papers, Vagelos has been elected to the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, a ...
, the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...
and the
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
. In 1995, Vagelos received the
NAS Award for Chemistry in Service to Society The NAS Award for Chemistry in Service to Society is awarded by the U.S. National Academy of Sciences "for contributions to chemistry, either in fundamental science or its application, that clearly satisfy a societal need." It has been awarded ev ...
and was inducted into the Junior Achievement U.S. Business Hall of Fame. In 1999, he became a recipient of both the Bower Award for Business Leadership, as well as the Othmer Gold Medal. In 2013, Vagelos was invited to speak at the first annual Stony Brook University ''Research Your Future'' Symposium.


River blindness

In the mid-1980s, Merck & Co. discovered the drug
ivermectin Ivermectin (, '' EYE-vər-MEK-tin'') is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. Approved for human use in 1987, today it is used to treat i ...
, capable of combatting the parasite that causes river blindness. At the time, the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level o ...
and the
World Bank The World Bank is an international financial institution that provides loans and grants to the governments of low- and middle-income countries for the purpose of pursuing capital projects. The World Bank is the collective name for the Inte ...
were conducting a campaign against the vector-borne disease in
West Africa West Africa or Western Africa is the westernmost region of Africa. The United Nations defines Western Africa as the 16 countries of Benin, Burkina Faso, Cape Verde, The Gambia, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Liberia, Mali ...
, and ivermectin was the most important drug in their arsenal. But the newly discovered drug was too expensive for those patients or their governments. Vagelos "wanted to see the drug widely used," so he influenced Merck & Co. to "make needed quantities of the drug available to these governments and patients, at no cost to them, for the treatment of onchocerciasis.” Over two decades, beginning in 1986, the drug reached more than 55 million people. The public health campaign was successful, and now river blindness is no longer a major public health issue in the savannah areas of West Africa.


Philanthropy

Together, Roy Vagelos and his wife Diana Vagelos donated over $15 million to the University of Pennsylvania to create the Roy and Diana Vagelos Laboratories. These funds also made possible the founding the Vagelos Scholars Program in Molecular Life Sciences, an intensive program offered to University of Pennsylvania freshmen. In addition, they donated funds to launch the Vagelos Program in Life Sciences and Management, a joint program between the Wharton School at the University of Pennsylvania and its College of Arts and Sciences. Later, they founded the Vagelos Integrated Program in Energy Research, supporting the necessity of energy research. In 2010, Vagelos, who had earned his medical degree at Columbia University, and Diana, an alumna of
Barnard College Barnard College of Columbia University is a private women's liberal arts college in the borough of Manhattan in New York City. It was founded in 1889 by a group of women led by young student activist Annie Nathan Meyer, who petitioned Columbia ...
at Columbia University, donated 50 million dollars to the Columbia College of Physicians and Surgeons, towards the construction of a new building named the Roy and Diana Vagelos Education Center; it opened in August 2016. In 2017, it was announced at the Crown Awards that the College of Physicians and Surgeons would be renamed the Columbia University Roy and Diana Vagelos College of Physicians and Surgeons in recognition of a $250 million gift given by Vagelos to the college. A substantial part of the donation ($150 million) would be used to endow a fund that will help eliminate student loans for medical students who qualify for financial aid. Altogether, the Vageloses have been responsible for about $450 million in philanthropy to Columbia's medical school. In 2022, the Vageloses donated $55 million to
Barnard College Barnard College of Columbia University is a private women's liberal arts college in the borough of Manhattan in New York City. It was founded in 1889 by a group of women led by young student activist Annie Nathan Meyer, who petitioned Columbia ...
to support the college's
STEM education Stem or STEM may refer to: Plant structures * Plant stem, a plant's aboveground axis, made of vascular tissue, off which leaves and flowers hang * Stipe (botany), a stalk to support some other structure * Stipe (mycology), the stem of a mushro ...
efforts. It is the largest donation in the college's 130-year history.


References


External links


How to Succeed in Business
review of ''Medicine, Science and Merck'', 2004, by Vagelos and Louis Galambos
The Future of the Pharmaceutical Industry, According to Roy Vagelos
Wharton School podcast from 2006

* * {{DEFAULTSORT:Vagelos, Roy American people of Greek descent Living people 1929 births American manufacturing businesspeople Businesspeople in the pharmaceutical industry People from Westfield, New Jersey Merck & Co. people Columbia University Vagelos College of Physicians and Surgeons alumni University of Pennsylvania alumni Washington University in St. Louis faculty Rahway High School alumni Members of the United States National Academy of Sciences American chief executives Members of the National Academy of Medicine