Oxolinic acid
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Oxolinic acid is a quinolone
antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of ...
developed in Japan in the 1970s.JP Patent 49138244 Dosages 12–20 mg/kg orally administered for five to ten days. The antibiotic works by inhibiting the enzyme
DNA gyrase DNA gyrase, or simply gyrase, is an enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrat ...
. It also acts as a
dopamine reuptake inhibitor A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopa ...
and has stimulant effects in mice.


See also

* Amfonelic acid *
Fluoroquinolone A quinolone antibiotic is a member of a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. They are used in human and veterinary medicine to treat bacterial infections, as wel ...


References

Quinolone antibiotics Dopamine reuptake inhibitors Carboxylic acids Nitrogen heterocycles Oxygen heterocycles Heterocyclic compounds with 3 rings {{antibiotic-stub