Northiaden, also known as ''N''-desmethyldosulepin, is the major

active metabolite An active metabolite is an active form of a drug after it has been processed by the body. Metabolites of drugs An active metabolite results when a drug is metabolized by the body into a modified form which continues to produce effects in the body ...

of the

tricyclic antidepressant Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants, which is important for the management of depression. They are second-line drugs next to SSRIs. TCAs were discovered in the early 1950s and wer ...

(TCA) dosulepin (dothiepin; Prothiaden).

References

{{Tricyclics Alpha-1 blockers Amines Antihistamines Dibenzothiepines H1 receptor antagonists Human drug metabolites Muscarinic antagonists Serotonin receptor antagonists Serotonin–norepinephrine reuptake inhibitors Tricyclic antidepressants