Nucleoporin 205 (Nup205) is a protein that in humans is encoded by the ''NUP205''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Function
Transport of macromolecules between the cytoplasm and nucleus occurs through
nuclear pore
A nuclear pore is a part of a large complex of proteins, known as a nuclear pore complex that spans the nuclear envelope, which is the double membrane surrounding the eukaryotic cell nucleus. There are approximately 1,000 nuclear pore complexe ...
complexes (NPCs) embedded in the
nuclear envelope. NPC's are composed of subcomplexes, and NUP205 is part of one such subcomplex.
It has also been recently shown that Nup205 is required for proper viral gene expression.
References
Further reading
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Nuclear pore complex
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