NE-CHMIMO (CHM-018) is an
indole-based
synthetic cannabinoid
Synthetic cannabinoids are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis plants attach. These novel psychoactive substances should not be confused with synthetic ...
that is presumed to be a potent
agonist
An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...
of the
CB1 receptor and has been sold online as a
designer drug. NE-CHMIMO is the 1-cyclohexylmethyl (instead of 1-pentyl) analogue of the first-generation
synthetic cannabinoid
Synthetic cannabinoids are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis plants attach. These novel psychoactive substances should not be confused with synthetic ...
JWH-018. The corresponding cyclohexylmethyl derivative of
JWH-081 had also been reported several months earlier.
Legal status
In the United States, all CB
1 receptor agonists of the 3-(1-naphthoyl)indole class such as NE-CHMIMO are
Schedule I Controlled Substances.
NE-CHMIMO is a controlled substance in Japan as of November 2019.
See also
References
Designer drugs
Naphthoylindoles
CB1 receptor agonists
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