''Mycobacterium wolinskyi'' is a rapidly growing mycobacterium most commonly seen in post-traumatic wound infections, especially those following open fractures and with associated

osteomyelitis Osteomyelitis (OM) is an infection of bone. Symptoms may include pain in a specific bone with overlying redness, fever, and weakness. The long bones of the arms and legs are most commonly involved in children e.g. the femur and humerus, while the ...

. ''Mycobacterium wolinskyi'' is clearly clinically significant, and occurs in the same settings as ''

Mycobacterium smegmatis ''Mycobacterium smegmatis'' is an acid-fast bacterial species in the phylum ''Actinomycetota'' and the genus ''Mycobacterium''. It is 3.0 to 5.0 µm long with a bacillus shape and can be stained by Ziehl–Neelsen method and the auramine-rh ...

'' and members of the ''

Mycobacterium fortuitum ''Mycobacterium fortuitum'' is a nontuberculous species of the phylum Actinomycetota (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus ''Mycobacterium''. Backgroun ...

'' complex; they differ from members of the ''

'' complex in the type of chronic lung disease they produce, with essentially all cases occurring in the setting of chronic lipoid

pneumonia Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severi ...

, either secondary to chronic oil ingestion or chronic aspiration (usually achalasia).

Etymology Etymology ()The New Oxford Dictionary of English (1998) – p. 633 "Etymology /ˌɛtɪˈmɒlədʒi/ the study of the class in words and the way their meanings have changed throughout time". is the study of the history of the Phonological chan ...

: Wolinsky, named after Emanuel Wolinsky in honour of, and in recognition for, significant contributions to the study of the non-tuberculous mycobacteria. *''Mycobacterium wolinskyi'' was previously known as ''

'' group 3.

Description

Microscopy *Gram-positive, nonmotile and acid-fast rods. Colony characteristics *Smooth to mucoid, off-white to cream coloured and nonpigmented colonies. *Visible growth in 2 to 4 days on Middlebrook 7H10 agar. Physiology *No pigment is produced and growth occurs at 30, 35 and 45 °C. *Isolates grow on MacConkey agar without crystal violet and in the presence of 5% NaCl, are negative for arylsulfatase activity at three days. *Positive for iron uptake and nitrate reductase. *They produce low-level semi-quantitative catalase activity that is stable at 68 °C, pH 7±0. *The type strain is susceptible to amikacin and sulfamethoxazole, intermediately susceptible to doxycycline and

ciprofloxacin Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. This includes bone and joint infections, intra abdominal infections, certain types of infectious diarrhea, respiratory tract infections, skin inf ...

, variably susceptible to cefmetazole, cefoxitin, chloramphenicol and clarithromycin, and resistant to isoniazid, rifampin and tobramycin.

Pathogenesis

*''M. wolinskyi'' causes human disease and is most commonly seen in post-traumatic wound infections, especially those following open fractures and with associated osteomyelitis.

Type strain

*The type strain, ATCC 700010T (MO739), was recovered from a post-surgical facial abscess in Switzerland. *Strain MO739 = ATCC 700010 = CCUG 47168 = CIP 106348 = DSM 44493 = JCM 13393.

References

*Brown B.A., 1999. Mycobacterium wolinskyi sp. nov. and Mycobacterium goodii sp. nov., two new rapidly growing species related to Mycobacterium smegmatis and associated with human wound infections: a cooperative study from the International Working Group on Mycobacterial Taxonomy. Int. J. Syst. Bacteriol., 49, 1493–1511.

External links

Type strain of ''Mycobacterium wolinskyi'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
Acid-fast bacilli wolinskyi Bacteria described in 1999 {{Mycobacterium-stub