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Chemical formul

Mycobacterium leprae was sensitive to dapsone (diaminodiphenylsulfone, the first effective treatment which was discovered for leprosy in the 1940s), but resistance against this antibiotic began to develop in the 1960s. Therapy with dapsone alone is now strongly contraindicated. Currently, a multidrug treatment (MDT) is recommended by the World Health Organization, including dapsone, rifampicin. and clofazimine (The two later were both discovered in the 1960s).[23] In patients receiving the MDT, a high proportion of the bacilli die within a short amount of time without immediate relief of symptoms. This suggests many symptoms of leprosy must be due in part to the presence of dead cells.

Treatment

Multidrug therapy (MDT) uses combinations of antibiotics that kill M. leprae including: dapsone, rifampin, clofazamine, fluoroquinolones, azithromycin, and minocycline. Antibiotics must be taken regularly until treatment is complete due to the fact M. leprae has the ability to grow back.[24]

A preventive measure of M. leprae is to avoid close contact with infectious people who are untreated.[25] Blindness, crippling of the hands and feet, and paralysis are all effects of nerve damage done by untreated M. leprae.

Multidrug therapy (MDT) uses combinations of antibiotics that kill M. leprae including: dapsone, rifampin, clofazamine, fluoroquinolones, azithromycin, and minocycline. Antibiotics must be taken regularly until treatment is complete due to the fact M. leprae has the ability to grow back.[24]

A preventive measure of M. leprae is to avoid close contact with infectious people who are untreated.[25] Blindness, crippling of the hands and feet, and paralysis are all effects of nerve damage done by untreated M. lep

A preventive measure of M. leprae is to avoid close contact with infectious people who are untreated.[25] Blindness, crippling of the hands and feet, and paralysis are all effects of nerve damage done by untreated M. leprae. Treatment does not reverse the nerve damage done, which is why it is recommended to get treated as soon as possible.[24] The Bacillus Calmette–Guérin vaccine offers a variable amount of protection against leprosy in addition to its main target of tuberculosis.[26]