Mycobacterium interjectum
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''Mycobacterium interjectum'' is a species of the phylum
Actinomycetota The ''Actinomycetota'' (or ''Actinobacteria'') are a phylum of all gram-positive bacteria. They can be terrestrial or aquatic. They are of great economic importance to humans because agriculture and forests depend on their contributions to s ...
(
Gram-positive In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall. Gram-positive bact ...
bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of prokaryotic microorganisms. Typically a few micrometr ...
with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium.


Name

Etymology Etymology ()The New Oxford Dictionary of English (1998) – p. 633 "Etymology /ˌɛtɪˈmɒlədʒi/ the study of the class in words and the way their meanings have changed throughout time". is the study of the history of the Phonological chan ...
: Phylogenetic position between ( la, interjectum) rapidly and slowly growing mycobacteria.


Description

''Mycobacterium interjectum is Gram-positive, nonmotile and
acid-fast Acid-fastness is a physical property of certain bacterial and eukaryotic cells, as well as some sub-cellular structures, specifically their resistance to decolorization by acids during laboratory staining procedures. Once stained as part of a sam ...
rods (0.6-1.0 µm x 0.7-2.0 µm). Filaments (up to 6.0 µm) possible.''


Colony characteristics

Dysgonic, smooth and scotochromogenic
colonies In modern parlance, a colony is a territory subject to a form of foreign rule. Though dominated by the foreign colonizers, colonies remain separate from the administration of the original country of the colonizers, the '' metropolitan state'' ...
(1–2 mm in diameter).


Physiology

*Slow growth on Löwenstein-Jensen medium at temperatures between 31
°C The degree Celsius is the unit of temperature on the Celsius scale (originally known as the centigrade scale outside Sweden), one of two temperature scales used in the International System of Units (SI), the other being the Kelvin scale. The ...
and 37 °C within 3–4 weeks. *Susceptible to rifampicin. *Resistant to
isoniazid Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. For la ...
and
ethambutol Ethambutol (EMB, E) is a medication primarily used to treat tuberculosis. It is usually given in combination with other tuberculosis medications, such as isoniazid, rifampicin and pyrazinamide. It may also be used to treat ''Mycobacterium avi ...
. Differential characteristics *Most closely related to ''M. simiae''. *
Phylogenetic In biology, phylogenetics (; from Greek φυλή/ φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups o ...
position between rapidly and slowly growing mycobacteria.


Pathogenesis

*Chronic
lymphadenitis Lymphadenopathy or adenopathy is a disease of the lymph nodes, in which they are abnormal in size or consistency. Lymphadenopathy of an inflammatory type (the most common type) is lymphadenitis, producing swollen or enlarged lymph nodes. In cl ...
* Biosafety level 2


Type strain

*First isolated from a lymph node of a child with chronic
lymphadenitis Lymphadenopathy or adenopathy is a disease of the lymph nodes, in which they are abnormal in size or consistency. Lymphadenopathy of an inflammatory type (the most common type) is lymphadenitis, producing swollen or enlarged lymph nodes. In cl ...
in
Germany Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwe ...
. Strain 4185/92 = ATCC 51457 = CCUG 37514 = DSM 44064


References

*Springer et al. 1993. Mycobacterium interjectum, a new species isolated from a patient with chronic lymphadenitis. J. Clin. Microbiol., 31, 3083–3089.


External links


Type strain of ''Mycobacterium interjectum'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
{{DEFAULTSORT:Mycobacterium Interjectum Acid-fast bacilli interjectum Bacteria described in 1995