Mycobacterium confluentis is a non-

pathogenic In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ ...

bacterium of the oral cavity.

Description

Gram-positive In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall. Gram-positive bacte ...

, nonmotile, acid-fast

coccobacillus A coccobacillus (plural coccobacilli), or bacilluscocco, is a type of bacterium with a shape intermediate between cocci (spherical bacteria) and bacilli (rod-shaped bacteria). Coccobacilli, then, are very short rods which may be mistaken for cocci ...

(0.5-0.8 μm x 0.7-1.7 μm), does not form

spore In biology, a spore is a unit of sexual or asexual reproduction that may be adapted for dispersal and for survival, often for extended periods of time, in unfavourable conditions. Spores form part of the life cycles of many plants, algae, f ...

s, capsules or aerial

hypha A hypha (; ) is a long, branching, filamentous structure of a fungus, oomycete, or actinobacterium. In most fungi, hyphae are the main mode of vegetative growth, and are collectively called a mycelium. Structure A hypha consists of one or ...

Physiology

*Rapid growth within 2 to 4 days on Löwenstein-Jensen media at 22 °C, 31 °C, 37 °C and 41 °C (optimum growth between 31 °C and 37 °C). *

In vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology an ...

susceptibility to

isoniazid Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. For l ...

ethambutol Ethambutol (EMB, E) is a medication primarily used to treat tuberculosis. It is usually given in combination with other tuberculosis medications, such as isoniazid, rifampicin and pyrazinamide. It may also be used to treat ''Mycobacterium avium ...

and

streptomycin Streptomycin is an antibiotic medication used to treat a number of bacterial infections, including tuberculosis, ''Mycobacterium avium'' complex, endocarditis, brucellosis, ''Burkholderia'' infection, plague, tularemia, and rat bite fever. Fo ...

Differential characteristics

*Differentiation from other thermotolerant

mycobacteria ''Mycobacterium'' is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis ('' M. tuberculosis'') and ...

by its inability to grow at temperatures of more than 41 °C. *Separation from other rapidly growing

by its susceptibility to antituberculotic drugs. *Differentiated from the

phenotypic In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological proper ...

closely related M. thermoresistibile by its inability to grow at 52 °C.

Pathogenesis

Not associated with

disease A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...

. Biosafety level 1.

Type strain

First isolated from

sputum Sputum is mucus that is coughed up from the lower airways (the trachea and bronchi). In medicine, sputum samples are usually used for a naked eye examination, microbiological investigation of respiratory infections and cytological investigations ...

Koblenz Koblenz (; Moselle Franconian language, Moselle Franconian: ''Kowelenz''), spelled Coblenz before 1926, is a German city on the banks of the Rhine and the Moselle, a multi-nation tributary. Koblenz was established as a Roman Empire, Roman mili ...

Germany Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwe ...

. strain 1389/90 = ATCC 49920 = CIP 105510 = DSM 44017 = JCM 13671.

References

*Kirschner et al. 1992. Mycobacterium confluentis sp. nov. Int. J. Syst. Bacteriol., 42, 257–262.

External links

Type strain of ''Mycobacterium confluentis'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
Acid-fast bacilli confluentis Bacteria described in 1992 {{Mycobacterium-stub