''Mycolicibacter arupensis'' (formerly ''Mycobacterium arupense'') is a slowly growing

mycobacterium ''Mycobacterium'' is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis ('' M. tuberculosis'') and ...

first isolated from soil and human sputum samples in Spain.

Etymology Etymology ()The New Oxford Dictionary of English (1998) – p. 633 "Etymology /ˌɛtɪˈmɒlədʒi/ the study of the class in words and the way their meanings have changed throughout time". is the study of the history of the Phonological chan ...

: arupense, pertaining to the ARUP Institute for Clinical and Experimental Pathology, where the type strain was characterized.

Description

Microscopy *Gram-positive, nonmotile and acid-fast rods (1–3 µm × 0.5–0.7 µm), mostly strong acid-fast. Colony characteristics * Colonies are eugonic, rough and nonpigmented. Physiology *Colonies occur within 5 days at 30 °C (optimum temperature, no growth at 45 °C) on Löwenstein-Jensen medium and on Middlebrook 7H10 agar and slowly (10–12 days) at 37 °C; no growth occurs at 42 °C. *No growth on

MacConkey agar MacConkey agar is a selective and differential culture medium for bacteria. It is designed to selectively isolate Gram-negative and enteric (normally found in the intestinal tract) bacteria and differentiate them based on lactose fermentation. ...

without

crystal violet Crystal violet or gentian violet, also known as methyl violet 10B or hexamethyl pararosaniline chloride, is a triarylmethane dye used as a histological stain and in Gram's method of classifying bacteria. Crystal violet has antibacterial, antif ...

. *The type strain is resistant to

D-cycloserine Cycloserine, sold under the brand name Seromycin, is a GABA transaminase inhibitor and an antibiotic, used to treat tuberculosis. Specifically it is used, along with other antituberculosis medications, for active drug resistant tuberculosis. It ...

streptomycin Streptomycin is an antibiotic medication used to treat a number of bacterial infections, including tuberculosis, ''Mycobacterium avium'' complex, endocarditis, brucellosis, ''Burkholderia'' infection, plague, tularemia, and rat bite fever. Fo ...

isoniazid Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. For l ...

(0.1 and 1 mg/L),

rifampin Rifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis (TB), ''Mycobacterium avium'' complex, leprosy, and Legionnaires’ disease. It is almost always used tog ...

, and thiacetazone and is susceptible to isoniazid (10 mg/L),

kanamycin Kanamycin A, often referred to simply as kanamycin, is an antibiotic used to treat severe bacterial infections and tuberculosis. It is not a first line treatment. It is used by mouth, injection into a vein, or injection into a muscle. Kanamycin ...

, and

capreomycin Capreomycin is an antibiotic which is given in combination with other antibiotics for the treatment of tuberculosis. Specifically it is a second line treatment used for active drug resistant tuberculosis. It is given by injection into a vein or ...

Pathogenesis

There are emerging reports of human pathogenesis caused by ''M. arupensis''. Pulmonary infection and tenosynovitis have been documented. A recent case of recurrent soft tissue abscess caused by ''M. arupensis'' has been identified.

References

External links

Type strain of ''Mycolicibacter arupensis'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
Acid-fast bacilli arupense Bacteria described in 2006 {{Mycobacterium-stub