Mucinous cystadenoma is a benign cystic tumor lined by a mucinous epithelium. It is a type of cystic

adenoma An adenoma is a benign tumor of epithelial tissue with glandular origin, glandular characteristics, or both. Adenomas can grow from many glandular organs, including the adrenal glands, pituitary gland, thyroid, prostate, and others. Some adenom ...

(

cystadenoma Cystadenoma (or "cystoma") is a type of cystic adenoma. When malignant, it is called cystadenocarcinoma. Classification When not otherwise specified, the ICD-O coding is 8440/0. However, the following classifications also exist: By form * sero ...

). Mucinous cystadenomata may arise in a number of locations; however, mucinous cystadenoma at different locations are not generally considered to be related to one another.

Overview

Mucinous cystadenomas may be found in the: *

Ovary The ovary is an organ in the female reproductive system that produces an ovum. When released, this travels down the fallopian tube into the uterus, where it may become fertilized by a sperm. There is an ovary () found on each side of the body. ...

— ovarian mucinous cystadenoma *

Pancreas The pancreas is an organ of the digestive system and endocrine system of vertebrates. In humans, it is located in the abdomen behind the stomach and functions as a gland. The pancreas is a mixed or heterocrine gland, i.e. it has both an end ...

—

pancreatic mucinous cystadenoma Pancreatic mucinous cystadenoma, also known as "mucinous cystadenoma of the pancreas", is a benign tumour of pancreas. It is one of the cystic lesions of the pancreas. Pathology Microscopy File:Mucinous cystadenoma of the pancreas 5.jpg, Mu ...

Peritoneum The peritoneum is the serous membrane forming the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids. It covers most of the intra-abdominal (or coelomic) organs, and is composed of a layer of mesoth ...

— peritoneal mucinous cystadenoma *

Liver The liver is a major Organ (anatomy), organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of proteins and biochemicals necessary for ...

— mucinous cystadenoma of the liver *

Vermiform appendix The appendix (or vermiform appendix; also cecal r caecalappendix; vermix; or vermiform process) is a finger-like, blind-ended tube connected to the cecum, from which it develops in the embryo. The cecum is a pouch-like structure of the large i ...

— appendiceal mucinous cystadenoma (see

)

Ovarian mucinous cystadenoma

Mucinous cystadenomas make up 15–20% of all ovarian tumors. They often become very large and can extend up into the abdomen. These tumors are usually evaluated using ultrasound, CT scan, or MRI. Findings on imaging studies are nonspecific. These ovarian tumors are usually multi-septated, cystic masses with thin walls. They also contain varying amounts of solid tissue which consists of proliferating stromal tissue, papillae, or malignant tumor cells. Benign mucinous cystadenomas compose 80% of mucinous ovarian tumors and 20–25% of benign ovarian tumors overall. The peak incidence occurs between 30 and 50 years of age. Benign tumors are bilateral in 5–10% of cases.

Macroscopy

File:Ovarian Mucinous Cystadenoma.jpg File:Mucinous Cystadenoma of Ovary (218889489).jpg file:Mucinous cystadenoma.jpg

Microscopy

File:Ovarian mucinous cystadenoma - alt -- low mag.jpg File:Ovarian mucinous cystadenoma -- low mag.jpg File:Ovarian mucinous cystadenoma -- intermed mag.jpg File:Ovarian mucinous cystadenoma - a2 -- intermed mag.jpg File:Ovarian mucinous cystadenoma - a2 -- high mag.jpg File:Ovarian mucinous cystadenoma - a3 -- high mag.jpg File:Ovarian mucinous cystadenoma -- high mag.jpg File:Mucinous cystadenoma of the pancreas 7.jpg

Types

Pancreatic

Pancreatic mucinous cystadenoma or mucinous cystadenoma of the pancreas (MCN) are a type of mucinous cystic neoplasm of the pancreas. The cure rate is very high in cases on benign cystic lesions, but the case changes if malignant changes ensue. Benign cystadenomas are the most common cystic tumors of the pancreas accounting for 75% of the cases. On an average, mucinous accounts for 40–50% of cystic tumors, and serous cytadenoma accounts for 30% of it. Mucinous cystadenomas are in the dital pancreas in about 80% of the cases and distal pancreatectomy is needed for resection. In 20% of the cases it is in the head of the pancreas. Earlier it was believed that MCN occurs exclusively in females who are middle aged. However, occasional occurrence in men have been reported, especially those who are 45 years of age or above.

Liver

A rare neoplasm, 95% cases occur in women, especially at the mean age of 45. Biliary cystadenoma and cystadenocarcinoma constitute less than 5% of intrahepatic cysts originating from the bile duct. Cystadenomas in liver are often confused with hydatid cyst as their appearance on various imaging techniques is nearly same. Treating cystadenomas as hydatid cyst has resulted in recurrence of the cyst.

Primary retroperitoneal

Cases of primary retroperitoneal mucinous cystadenoma (PRMC) are extremely rare. However, they are observed more frequently in women, with only four cases having been found in men. Even though mucinous cystadenoma are common ovarian tumor, what makes PRMC so rare is their retroperitoneal location. PRMC and benign mucinous cystadenoma of the ovary are microscopically similar. Both are multiloculated cystic neoplasms and are lined by a single layer of tall columnar cells with a clear basal nucleus and cytoplasm. Both of them have identical histochemical and ultrastructural features. Flat to low cuboidal cells, resembling mesothelial cells, in the lining interspersed between columnar cells in the same area is the only histological difference between the two tumors.

References

External links

{{Genital neoplasia Types of neoplasia