Mike may refer to:

Animals

* Mike (cat), cat and guardian of the British Museum * Mike the Headless Chicken, chicken that lived for 18 months after his head had been cut off * Mike (chimpanzee), a chimpanzee featured in several books and documentaries

Arts

* Mike (miniseries), a 2022 Hulu limited series based on the life of American boxer Mike Tyson * Mike (2022 film), a Malayalam film produced by John Abraham * Mike (album), ''Mike'' (album), an album by Mike Mohede * Mike (1926 film), ''Mike'' (1926 film), an American film * MIKE (musician), American rapper, songwriter and record * Mike (novel), ''Mike'' (novel), a 1909 novel by P. G. Wodehouse * Mike (song), "Mike" (song), by Elvana Gjata and Ledri Vula featuring John Shahu * Mike (Twin Peaks), Mike (''Twin Peaks''), a character from ''Twin Peaks'' * "Mike", a song by Xiu Xiu from their 2004 album ''Fabulous Muscles''

Businesses

* Mike (cellular network), a defunct Canadian cellular network * Mike and Ike, a candies brand

Military

* MIKE Force, a unit in the Vietnam War * Ivy Mike, the first test of a full-scale thermonuclear weapon

Technology

* Microphone * Micrometer (device) * MIKE2.0 methodology, open source delivery methodology for enterprise information management consultants

Other uses