Microsatellite enrichment is a method in
molecular biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physi ...
used for enriching the amount of
microsatellite sequences in a
DNA sample. This can be achieved by designing
oligonucleotide
Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids ...
probes that
hybridize
Hybridization (or hybridisation) may refer to:
*Hybridization (biology), the process of combining different varieties of organisms to create a hybrid
*Orbital hybridization, in chemistry, the mixing of atomic orbitals into new hybrid orbitals
*Nu ...
with the repeats in the microsatellites and then pull out the probe/microsatellite complexes from the solution.
This has been shown to be a cost-effective method to sample the
genetic diversity in non-model organisms.
References
Molecular biology techniques
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