Meprylcaine (also known as Epirocaine and Oracaine) is a

local anesthetic A local anesthetic (LA) is a medication that causes absence of pain sensation. In the context of surgery, a local anesthetic creates an absence of pain in a specific location of the body without a loss of consciousness, as opposed to a general a ...

with stimulant properties that is structurally related to dimethocaine. Meprylcaine has a relatively potent inhibitory action on the

monoamine transporter Monoamine transporters (MATs) are protein structures that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters. Three major classes of MATs (SERT, DAT, NET) are responsible fo ...

and inhibits the reuptake of dopamine,

norepinephrine Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as both a hormone and neurotransmitter. The name "noradrenaline" (from Latin '' ad' ...

and serotonin.

Synthesis

The 2-methyl-2-(propylamino)propan-1-ol 5968-10-0(1) is treated with base and then with

Benzoyl chloride Benzoyl chloride, also known as benzenecarbonyl chloride, is an organochlorine compound with the formula . It is a colourless, fuming liquid with an irritating odour, and consists of a benzene ring () with an acyl chloride () substituent. It is ...

(2), completing the synthesis of Meprycaine (3).

References

Local anesthetics Benzoate esters Serotonin–norepinephrine–dopamine reuptake inhibitors Stimulants {{nervous-system-drug-stub