Masoprocol is an
antineoplastic drug used to treat skin growths caused by sun exposure. It is the
meso
Meso or mesos may refer to:
* Apache Mesos, a computer clustering management platform
* Meso, in-game currency for the massively multiplayer online role-playing game '' MapleStory''
* Meso compound, a stereochemical classification in chemistry
* ...
form of
nordihydroguaiaretic acid
Nordihydroguaiaretic acid, informally abbreviated NDGA in research articles, is a classic lignan, a phenylpropane dimer linked by a bond between positions C8 and C8′, as opposed to a neolignan. It is a natural compound found in the creosote bush ...
that is taken by mouth. The substance is being studied in the treatment of prostate cancer.
Masoprocol is also called NDGA, and Actinex.
Mechanism
Nordihydroguaiaretic acid is an antioxidant, and it may block certain enzymes needed for tumor growth.
It is a
lipoxygenase inhibitor Arachidonate 5-lipoxygenase inhibitors are compounds that slow or stop the action of the arachidonate 5-lipoxygenase (5-lipoxygenase or 5-LOX) enzyme, which is responsible for the production of inflammatory leukotrienes. The overproduction of leukot ...
.
References
External links
MedlinePlus Drug InformationActinexentry in the public domain NCI Cancer Dictionary
Antineoplastic drugs
Catechols
{{antineoplastic-drug-stub